生藥學研究所

2015

卵巢良性腫瘤的中醫治療病例報告

Bo-Feng, W. & Tai, C-J., 2015, 於: 中醫婦科醫學雜誌. 19, p. 52-62 11 p.

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2014

Acacetin inhibits glutamate release and prevents kainic acid-induced neurotoxicity in rats

Lin, T. Y., Huang, W. J., Wu, C. C., Lu, C. W. & Wang, S. J., 2月 10 2014, 於: PLoS One. 9, 2, e88644.

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40 引文斯高帕斯（Scopus）

Adjunctive traditional Chinese medicine therapy improves survival in patients with advanced breast cancer: A population-based study

Lee, Y-W., Chen, T-L., Shih, Y. R. V., Tsai, C. L., Chang, C-C., Liang, H-H., Tseng, S-H., Chien, S-C. & Wang, C-C., 5月 1 2014, 於: Cancer. 120, 9, p. 1338-1344 7 p.

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98 引文斯高帕斯（Scopus）

A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies

Huang, W. J., Tang, Y. A., Chen, M. Y., Wang, Y. J., Hu, F. H., Wang, T. W., Chao, S. W., Chiu, H. W., Yeh, Y. L., Chang, H. Y., Juan, H. F., Lin, P. & Wang, Y. C., 4月 28 2014, 於: Cancer Letters. 346, 1, p. 84-93 10 p.

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21 引文斯高帕斯（Scopus）

Aliphatic phenolic ethers from trichobotrys effusa

Chen, J. J., Wang, S. W., Hsiao, H. Y., Lee, M. S., Ju, Y. M., Kuo, Y. H. & Li, Z-H., 5月 23 2014, 於: Journal of Natural Products. 77, 5, p. 1097-1101 5 p.

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4 引文斯高帕斯（Scopus）

A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i

Yu, C. C., Pan, S. L., Chao, S. W., Liu, S. P., Hsu, J. L., Yang, Y. C., Li, T. K., Huang, W. J. & Guh, J. H., 8月 1 2014, 於: Biochemical Pharmacology. 90, 3, p. 320-330 11 p.

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28 引文斯高帕斯（Scopus）

Anoxic androgen degradation by the denitrifying bacterium Sterolibacterium denitrificans via the 2,3-seco pathway

Wang, P. H., Yu, C. P., Li, Z-H., Lin, C. W., Ismail, W., Wey, S. P., Kuo, A. T. & Chiang, Y. R., 2014, 於: Applied and Environmental Microbiology. 80, 11, p. 3442-3452 11 p.

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31 引文斯高帕斯（Scopus）

Anti-inflammatory effects of vitis thunbergii var. taiwaniana on knee damage associated with arthritis

Tsai, C. F., Wang, K. T., Chen, L. G., Lee, C. J., Tseng, S. H. & Wang, C. C., 4月 1 2014, 於: Journal of Medicinal Food. 17, 4, p. 479-486 8 p.

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14 引文斯高帕斯（Scopus）

Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorin hydrolysis and its analogue, Gln-Trp

Han, C. H., Lin, Y. S., Lin, S. Y. & Hou, W. C., 2014, 於: Food Chemistry. 147, p. 195-202 8 p.

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33 引文斯高帕斯（Scopus）

Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

Chin, Y. T., Hsieh, M. T., Yang, S. H., Tsai, P. W., Wang, S. H., Wang, C. C., Lee, Y. S., Cheng, G. Y., HuangFu, W. C., London, D., Tang, H. Y., Fu, E., Yen, Y., Liu, L. F., Lin, H. Y. & Davis, P. J., 2014, 於: Oncotarget. 5, 24, p. 12891-12907 17 p.

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64 引文斯高帕斯（Scopus）

Antitumor effects and biological mechanism of action of the aqueous extract of the camptotheca acuminata fruit in human endometrial carcinoma cells

Lin, C. S., Chen, P. C., Wang, C. K., Wang, C-W., Chang, Y. J., Tai, C. J. & Tai, C. J., 2014, 於: Evidence-based Complementary and Alternative Medicine. 2014, 564810.

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16 引文斯高帕斯（Scopus）

Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential

Wang, S. C., Li, Z-H., Hsu, C. H., Chang, Y. J., Chang, M. S., Wang, Y. C., Ho, Y. S., Wen, W. C. & Lin, R. K., 6月 18 2014, 於: Journal of Agricultural and Food Chemistry. 62, 24, p. 5625-5635 11 p.

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39 引文斯高帕斯（Scopus）

Asn-Trp dipeptides improve the oxidative stress and learning dysfunctions in D-galactose-induced BALB/c mice

Han, C. H., Lin, Y. S., Lee, T. L., Liang, H. J. & Hou, W. C., 2014, 於: Food and Function. 5, 9, p. 2228-2236 9 p.

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19 引文斯高帕斯（Scopus）

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 5月 22 2014, 於: Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

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67 引文斯高帕斯（Scopus）

Biodistribution profiling of the chemical modified hyaluronic acid derivatives used for oral delivery system

Hsieh, C. M., Huang, Y. W., Sheu, M. T. & Ho, H. O., 2014, 於: International Journal of Biological Macromolecules. 64, p. 45-52 8 p.

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18 引文斯高帕斯（Scopus）

Carbamazepine attenuates inducible nitric oxide synthase expression through Akt inhibition in activated microglial cells

Wang, C. H., Hsiao, C. J., Lin, Y. N., Wu, J. W., Kuo, Y. C., Lee, C. K. & Hsiao, G., 11月 1 2014, 於: Pharmaceutical Biology. 52, 11, p. 1451-1459 9 p.

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23 引文斯高帕斯（Scopus）

Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption

Hsiao, C. J., Hsiao, G., Chen, W. L., Wang, S. W., Chiang, C. P., Liu, L. Y., Guh, J. H., Li, Z-H. & Chung, C. L., 4月 25 2014, 於: Journal of Natural Products. 77, 4, p. 758-765 8 p.

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46 引文斯高帕斯（Scopus）

Characterizations of plasticized polymeric film coatings for preparing multiple-unit floating drug delivery systems (muFDDSs) with controlled-release characteristics

Hung, S. F., Hsieh, C. M., Chen, Y. C., Wang, Y. C., Ho, H. O. & Sheu, M. T., 6月 26 2014, 於: PLoS ONE. 9, 6, e100321.

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13 引文斯高帕斯（Scopus）

Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler

Tseng, S. H., Sung, C. H., Chen, L. G., Lai, Y. J., Chang, W. S., Sung, H. C. & Wang, C. C., 1月 10 2014, 於: Journal of Ethnopharmacology. 151, 1, p. 352-360 9 p.

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42 引文斯高帕斯（Scopus）

Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents

Mehndiratta, S., Chiang, Y-F., Lai, M-J., Lee, H. Y., Chen, M. C., Kuo, C-C., Chang, C-Y., Chang, J-Y. & Liou, J. P., 9月 1 2014, 於: Bioorganic and Medicinal Chemistry. 22, 17, p. 4917-4923 7 p.

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9 引文斯高帕斯（Scopus）

Cucurbitane-type glycosides from the fruits of Momordica charantia and their hypoglycaemic and cytotoxic activities

Zhang, L. J., Liaw, C. C., Hsiao, P. C., Huang, H. C., Lin, M. J., Lin, Z. H., Hsu, F. L. & Kuo, Y. H., 2014, 於: Journal of Functional Foods. 6, 1, p. 564-574 11 p.

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25 引文斯高帕斯（Scopus）

Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: An in vitro and in vivo study

Li, P. C., Pan, C. H., Sheu, M. J., Wu, C. C., Ma, W. F. & Wu, C. H., 5月 13 2014, 於: PLoS One. 9, 5, e96927.

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22 引文斯高帕斯（Scopus）

Detection of trace ink compounds in erased handwritings using electrospray-assisted laser desorption ionization mass spectrometry

Kao, Y. Y., Cheng, S. C., Cheng, C. N., Shiea, J. & Ho, H. O., 2014, 於: Journal of Mass Spectrometry. 49, 6, p. 445-451 7 p.

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14 引文斯高帕斯（Scopus）

Development of an anti-methoxy poly(ethylene glycol) (α-mPEG) cell-based capture system to measure mPEG and mPEGylated molecules

Chuang, K. H., Kao, C. H., Roffler, S. R., Lu, S. J., Cheng, T. C., Wang, Y. M., Chuang, C. H., Hsieh, Y. C., Wang, Y. T., Wang, J. Y., Weng, K. Y. & Cheng, T. L., 10月 14 2014, 於: Macromolecules. 47, 19, p. 6880-6888 9 p.

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8 引文斯高帕斯（Scopus）

Diterpene glycosides and polyketides from xylotumulus gibbisporus

Chang, Y. C., Lu, C. K., Chiang, Y. R., Wang, G. J., Ju, Y. M., Kuo, Y. H. & Li, Z-H., 4月 25 2014, 於: Journal of Natural Products. 77, 4, p. 751-757 7 p.

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26 引文斯高帕斯（Scopus）

DNMT3B overexpression by deregulation of FOXO3a-mediated transcription repression and MDM2 overexpression in lung cancer

Yang, Y. C., Tang, Y. A., Shieh, J. M., Lin, R. K., Hsu, H. S. & Wang, Y. C., 9月 2014, 於: Journal of Thoracic Oncology. 9, 9, p. 1305-1315 11 p.

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34 引文斯高帕斯（Scopus）

Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer

Lin, R. K. & Wang, Y. C., 8月 19 2014, 於: Cell and Bioscience. 4, 1, 46.

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76 引文斯高帕斯（Scopus）

Effects of yam tuber protein, dioscorin, on attenuating oxidative status and learning dysfunction in d-galactose-induced BALB/c mice

Han, C. H., Lin, Y. F., Lin, Y. S., Lee, T. L., Huang, W. J., Lin, S. Y. & Hou, W. C., 3月 2014, 於: Food and Chemical Toxicology. 65, p. 356-363 8 p.

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30 引文斯高帕斯（Scopus）

Evaluation of the antihyperuricemic activity of phytochemicals from Davallia formosana by enzyme assay and hyperuricemic mice model

Chen, C. Y., Huang, C. C., Tsai, K. C., Huang, W. J., Huang, W. C., Hsu, Y. C. & Hsu, F-L., 2014, 於: Evidence-based Complementary and Alternative Medicine. 2014, 873607.

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13 引文斯高帕斯（Scopus）

Glucose-regulated protein 94 modulates the therapeutic efficacy to taxane in cervical cancer cells

Tai, C. J., Wang, J. W., Su, H. Y., Tai, C. J., Wang, C. K., Wu, C. T., Lien, Y. C. & Chang, Y. J., 1月 2014, 於: Tumor Biology. 35, 1, p. 403-410 8 p.

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9 引文斯高帕斯（Scopus）

High-throughput sorting of the highest producing cell via a transiently protein-anchored system

Chuang, K. H., Hsieh, Y. C., Chiang, I. S., Chuang, C. H., Kao, C. H., Cheng, T. C., Wang, Y. T., Lin, W. W., Chen, B. M., Roffler, S. R., Huang, M. Y. & Cheng, T. L., 7月 18 2014, 於: PLoS One. 9, 7, e102569.

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7 引文斯高帕斯（Scopus）

Identification of trans, trans-2,4-Decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry

Pan, K. L., Huang, W. J., Hsu, M. H., Lee, H. L., Liu, H. J., Cheng, C. W., Tsai, M. H., Shen, M. Y. & Lin, P., 10月 20 2014, 於: Chemical Research in Toxicology. 27, 10, p. 1707-1719 13 p.

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9 引文斯高帕斯（Scopus）

Inhibitory effect of dihydroaustrasulfone alcohol on the migration of human non-small cell lung carcinoma A549 cells and the antitumor effect on a Lewis lung carcinoma-bearing tumor model in C57BL/6J mice

Chen, S. C., Chien, Y. C., Pan, C. H., Sheu, J. H., Chen, C. Y. & Wu, C. H., 1月 2014, 於: Marine Drugs. 12, 1, p. 196-213 18 p.

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20 引文斯高帕斯（Scopus）

Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies

Su, Y. C., Al-Qaisi, T. S., Tung, H. Y., Cheng, T. L., Chuang, K. H., Chen, B. M. & Roffler, S. R., 2014, 於: mAbs. 6, 4, p. 1069-1083 15 p.

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7 引文斯高帕斯（Scopus）

New isoflavones and anti-inflammatory constituents from the fruits of Cnidium monnieri

Li, Z-H., Chen, Y. C., Hwang, T. L., Shu, C. W., Sung, P. J., Lim, Y. P., Kuo, W. L. & Chen, J. J., 3月 28 2014, 於: International Journal of Molecular Sciences. 15, 6, p. 9566-9578 13 p.

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14 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing smad2 and akt pathways in human colorectal adenocarcinoma cells

Liu, L. Y., Huang, W. J., Ho, F. M., Lin, R-J., Lin, S. Y., Suk, F. M. & Liang, Y. C., 6月 25 2014, 於: Chemico-Biological Interactions. 217, p. 1-8 8 p.

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13 引文斯高帕斯（Scopus）

NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells

Wu, S. Y., Pan, S. L., Xiao, Z. Y., Hsu, J. L., Chen, M. C., Lee, K. H. & Teng, C. M., 11月 5 2014, 於: PLoS ONE. 9, 11, e112220.

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13 引文斯高帕斯（Scopus）

NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway

Chung, Y. L., Pan, C. H., Liou, W. H., Sheu, M. J., Lin, W. H., Chen, T. C., Huang, H. S. & Wu, C. H., 2014, 於: Journal of Pharmacological Sciences. 124, 1, p. 7-17 11 p.

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12 引文斯高帕斯（Scopus）

One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles

Kao, C. H., Wang, J. Y., Chuang, K. H., Chuang, C. H., Cheng, T. C., Hsieh, Y. C., Tseng, Y. L., Chen, B. M., Roffler, S. R. & Cheng, T. L., 12月 1 2014, 於: Biomaterials. 35, 37, p. 9930-9940 11 p.

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43 引文斯高帕斯（Scopus）

Osteoporosis increases subsequent risk of gallstone: A nationwide population-based cohort study in Taiwan

Klahan, S., Kuo, C. N., Chien, S-C., Lin, Y. W., Lin, C. Y., Lin, C. H., Chang, W. C., Lin, C. I., Hung, K. S. & Chang, W. P., 11月 18 2014, 於: BMC Gastroenterology. 14, 1, 192.

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4 引文斯高帕斯（Scopus）

Pharmacological effects of "Jutsu" (Atractylodis rhizome and Atractylodis lanceae rhizome) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced head twitch response in mice (I)

Murayama, C., Wang, C. C., Michihara, S. & Norimoto, H., 9月 18 2014, 於: Molecules. 19, 9, p. 14979-14986 8 p.

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6 引文斯高帕斯（Scopus）

Physical and dissolution characterization of cilostazol solid dispersions prepared by hot melt granulation (HMG) and thermal adhesion granulation (TAG) methods

Chen, Y. C., Ho, H. O., Chiou, J. D. & Sheu, M. T., 10月 1 2014, 於: International Journal of Pharmaceutics. 473, 1-2, p. 458-468 11 p.

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22 引文斯高帕斯（Scopus）

Stimulation of osteogenic activity in human osteoblast cells by edible Uraria crinita

Mao, Y. W., Lin, R. D., Hung, H. C. & Lee, M. H., 6月 18 2014, 於: Journal of Agricultural and Food Chemistry. 62, 24, p. 5581-5588 8 p.

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19 引文斯高帕斯（Scopus）

Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo

Chen, C. H., Chen, M. C., Wang, J. C., Tsai, A. C., Chen, C. S., Liou, J. P., Pan, S. L. & Teng, C. M., 2014, 於: Clinical Cancer Research. 20, 5, p. 1274-1287 14 p.

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44 引文斯高帕斯（Scopus）

Thrombomodulin mediates the migration of cervical cancer cells through the regulation of epithelial-mesenchymal transition biomarkers

Tai, C-J., Cheng, C-W., Su, H. Y., Chen, W-Y., Wu, C. T., Lin, F-Y., Wang, C. K., Tai, C-J. & Wei, P-L., 1月 2014, 於: Tumor Biology. 35, 1, p. 47-54 8 p.

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10 引文斯高帕斯（Scopus）

Two new acidic diterpenoids from the heartwood of pinus massoniana LAMB.

Mohamed, H. A., Hsieh, C. L., Hsu, C., Kuo, C. C., Chang, H. S., Lee, C. K., Lee, T. H., Wu, J. B., Chang, C. I. & Kuo, Y. H., 8月 2014, 於: Helvetica Chimica Acta. 97, 8, p. 1146-1151 6 p.

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8 引文斯高帕斯（Scopus）

Vasorelaxing and antihypertensive activities of synthesized peptides derived from computer-aided simulation of pepsin hydrolysis of yam dioscorin

Lin, Y. S., Lu, Y. L., Wang, G. J., Liang, H. J. & Hou, W. C., 6月 7 2014, 於: Botanical Studies. 55, 1, 49.

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10 引文斯高帕斯（Scopus）

2013

A comparative study of symptoms and quality of life among patients with breast cancer receiving target, chemotherapy, or combined therapy

Huang, S. M., Tai, C-J., Lin, K. C., Tai, C-J., Tseng, L. M. & Chien, L. Y., 7月 2013, 於: Cancer Nursing. 36, 4, p. 317-325 9 p.

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16 引文斯高帕斯（Scopus）

Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

Li, Z-H., Chen, Y. C., Lee, C. K., Chang, H. S., Kuo, C. C., Chao, C. Y., Lin, J. J., Lo, L. C. & Kuo, Y. H., 6月 2013, 於: Natural Product Communications. 8, 6, p. 827-828 2 p.

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6 引文斯高帕斯（Scopus）

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma

Lin, Y. M., Velmurugan, B. K., Yeh, Y. L., Tu, C. C., Ho, T. J., Lai, T-I., Tsai, C. H., Tsai, F. J., Tsai, C. H. & Huang, C. Y., 12月 2013, 於: Oncology Reports. 30, 6, p. 3027-3031 5 p.

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25 引文斯高帕斯（Scopus）

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