生藥學研究所

2015

Caesarean delivery before 39 weeks associated with selecting an auspicious time for birth in Taiwan

Chu, K. H., Lee, Y. H., Tai, C. J., Lin, Y. H., Huang, C. M. & Chien, L. Y., 9月 1 2015, 於: Women and Birth. 28, 3, p. e52-e56

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7 引文斯高帕斯（Scopus）

Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan

Chen, C. Y., Chiu, F. Y., Lin, Y., Huang, W. J., Hsieh, P. S. & Hsu, F-L., 1月 22 2015, 於: International journal of molecular sciences. 16, 2, p. 2497-2516 20 p.

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18 引文斯高帕斯（Scopus）

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C-W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., 11月 1 2015, 於: Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

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27 引文斯高帕斯（Scopus）

Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering

Chen, Y. C., Chen, R. N., Jhan, H. J., Liu, D. Z., Ho, H. O., Mao, Y., Kohn, J. & Sheu, M. T., 9月 1 2015, 於: Tissue Engineering - Part C: Methods. 21, 9, p. 971-986 16 p.

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74 引文斯高帕斯（Scopus）

Direct coating of culture medium from cells secreting classical swine fever virus E2 antigen on ELISA plates for detection of E2-specific antibodies

Cheng, T. C., Pan, C. H., Chen, C. S., Chuang, K. H., Chuang, C. H., Huang, C. C., Chu, Y. Y., Yang, Y. C., Chu, P. Y., Kao, C. H., Hsieh, Y. C. & Cheng, T. L., 7月 1 2015, 於: Veterinary Journal. 205, 1, p. 107-109 3 p.

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7 引文斯高帕斯（Scopus）

Discovery of akt kinase inhibitors through structure-based virtual screening and their evaluation as potential anticancer agents

Chuang, C. H., Cheng, T. C., Leu, Y. L., Chuang, K. H., Tzou, S. C. & Chen, C. S., 2月 2 2015, 於: International journal of molecular sciences. 16, 2, p. 3202-3212 11 p.

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32 引文斯高帕斯（Scopus）

Discovery of specific inhibitors for intestinal E. coli β -glucuronidase through in silico virtual screening

Cheng, T. C., Chuang, K. H., Roffler, S. R., Cheng, K. W., Leu, Y. L., Chuang, C. H., Huang, C. C., Kao, C. H., Hsieh, Y. C., Chang, L. S., Cheng, T. L. & Chen, C. S., 2015, 於: Scientific World Journal. 2015, 740815.

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10 引文斯高帕斯（Scopus）

DUSP1 expression induced by HDAC1 inhibition mediates gefitinib sensitivity in non-small cell lung cancers

Lin, Y. C., Lin, Y. C., Shih, J. Y., Huang, W. J., Chao, S. W., Chang, Y. L. & Chen, C. C., 1月 15 2015, 於: Clinical Cancer Research. 21, 2, p. 428-438 11 p.

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35 引文斯高帕斯（Scopus）

Early viral entry assays for the identification and evaluation of antiviral compounds

Tai, C. J., Li, C. L., Tai, C. J., Wang, C. K. & Lin, L. T., 10月 29 2015, 於: Journal of Visualized Experiments. 2015, 104, e53124.

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33 引文斯高帕斯（Scopus）

Effective Energy Transfer via Plasmon-Activated High-Energy Water Promotes Its Fundamental Activities of Solubility, Ionic Conductivity, and Extraction at Room Temperature

Yang, C. P., Chen, H. C., Wang, C. C., Tsai, P. W., Ho, C. W. & Liu, Y. C., 12月 10 2015, 於: Scientific Reports. 5, 18152.

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14 引文斯高帕斯（Scopus）

Effects of hot-water extracts from Ganoderma lucidum residues and solid-state fermentation residues on prebiotic and immune-stimulatory activities in vitro and the powdered residues used as broiler feed additives in vivo

Liu, Y-H., Lin, Y-S., Lin, K-L., Lu, Y-L., Chen, C-H., Chien, M-Y., Shang, H-F., Lin, S-Y. & Hou, W-C., 2015, 於: Botanical Studies. 56, 1, p. 1-10 10 p.

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14 引文斯高帕斯（Scopus）

Effects of yam dioscorin interventions on improvements of the metabolic syndrome in high-fat diet-induced obese rats

Shih, S-L., Lin, Y-S., Lin, S-Y. & Hou, W-C., 2015, 於: Botanical Studies. 56, 1, p. 1-9 9 p.

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15 引文斯高帕斯（Scopus）

Efficacy of antioxidants as a complementary and alternative medicine (CAM) in combination with the chemotherapeutic agent doxorubicin

Sheu, M. T., Jhan, H. J., Hsieh, C. M., Wang, C. J. & Ho, H. O., 3月 17 2015, 於: Integrative Cancer Therapies. 14, 2, p. 184-195 12 p.

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36 引文斯高帕斯（Scopus）

Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by honokiol in glioblastoma multiforme cells

Lai, I. C., Shih, P. H., Yao, C-J., Yeh, C-T., Wang-Peng, J., Lui, T-N., Chuang, S. E., Hu, T. S., Lai, T-Y. & Lai, G-M., 3月 12 2015, 於: PLoS ONE. 10, 3, e0114830.

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26 引文斯高帕斯（Scopus）

FCGR2A promoter methylation and risks for intravenous immunoglobulin treatment responses in kawasaki disease

Kuo, H. C., Hsu, Y. W., Wu, M. S., Woon, P. Y., Wong, H. S. C., Tsai, L. J., Lin, R. K., Klahan, S., Hsieh, K. S. & Chang, W. C., 2015, 於: Mediators of Inflammation. 2015, 564625.

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16 引文斯高帕斯（Scopus）

Ferulic Acid Induces Th1 Responses by Modulating the Function of Dendritic Cells and Ameliorates Th2-Mediated Allergic Airway Inflammation in Mice

Lee, C. C., Wang, C. C., Huang, H. M., Lin, C. L., Leu, S. J. & Lee, Y. L., 2015, 於: Evidence-based Complementary and Alternative Medicine. 2015, 678487.

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31 引文斯高帕斯（Scopus）

Formulation and process optimization of multiparticulate pulsatile system delivered by osmotic pressure-activated rupturable membrane

Hung, S. F., Hsieh, C. M., Chen, Y. C., Lin, C. M., Ho, H. O. & Sheu, M. T., 3月 1 2015, 於: International Journal of Pharmaceutics. 480, 1-2, p. 15-26 12 p.

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11 引文斯高帕斯（Scopus）

Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways

Lin, Y. S., Wu, W. C., Lin, S. Y. & Hou, W. C., 2015, 於: Amino Acids. 47, 3, p. 617-625 9 p.

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12 引文斯高帕斯（Scopus）

HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation

Qi, J., Singh, S., Hua, W. K., Cai, Q., Chao, S. W., Li, L., Liu, H., Ho, Y., McDonald, T., Lin, A., Marcucci, G., Bhatia, R., Huang, W. J., Chang, C. I. & Kuo, Y. H., 11月 5 2015, 於: Cell Stem Cell. 17, 5, p. 597-610 14 p.

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73 引文斯高帕斯（Scopus）

Hispidulin, a constituent of Clerodendrum inerme that remitted motor tics, alleviated methamphetamine-induced hyperlocomotion without motor impairment in mice

Huang, W. J., Lee, H. J., Chen, H. L., Fan, P. C., Ku, Y. L. & Chiou, L. C., 5月 26 2015, 於: Journal of Ethnopharmacology. 166, p. 18-22 5 p.

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28 引文斯高帕斯（Scopus）

Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer

Wei, T. T., Lin, Y. C., Lin, P. H., Shih, J. Y., Chou, C. W., Huang, W. J., Yang, Y. C., Hsiao, P. W. & Chen, C. C., 2015, 於: Oncotarget. 6, 14, p. 12481-12492 12 p.

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12 引文斯高帕斯（Scopus）

Integrated Treatment of Aqueous Extract of Solanum nigrum -Potentiated Cisplatin- and Doxorubicin-Induced Cytotoxicity in Human Hepatocellular Carcinoma Cells

Wang, C. K., Lin, Y. F., Tai, C. J., Wang, C. W., Chang, Y. J., Choong, C. Y., Lin, C. S., Tai, C. J. & Chang, C. C., 2015, 於: Evidence-based Complementary and Alternative Medicine. 2015, 675270.

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26 引文斯高帕斯（Scopus）

K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2

Pan, C. H., Lin, W. H., Chien, Y. C., Liu, F. C., Sheu, M. J., Kuo, Y. H. & Wu, C. H., 1月 5 2015, 於: Toxicology and Applied Pharmacology. 282, 2, p. 215-226 12 p.

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6 引文斯高帕斯（Scopus）

Kinsenoside-mediated lipolysis through an AMPK-dependent pathway in C3H10T1/2 adipocytes: Roles of AMPK and PPARα in the lipolytic effect of kinsenoside

Cheng, K. T., Wang, Y. S., Chou, H. C., Chang, C-C., Lee, C. K. & Juan, S. H., 5月 10 2015, 於: Phytomedicine. 22, 6, p. 641-647 7 p.

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30 引文斯高帕斯（Scopus）

Learning the fundamentals of traditional Chinese medicine by using computer courseware: A preliminary study

Shih, Y. C., Lee, Y-W., Tseng, S-H., Chien, S-C. & Wang, C-C., 2015, 於: Indian Journal of Pharmaceutical Education and Research. 49, 1, p. 18-25 8 p.

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2 引文斯高帕斯（Scopus）

Meditative qigong relieved symptom severity and interference among patients with breast carcinoma receiving chemotherapy

Chen, P. H., Huang, S. M., Tai, C. J., Chien, L. Y., Lien, P. J. & Chen, Y. H., 12月 1 2015, 於: European Journal of Integrative Medicine. 7, 6, p. 617-622 6 p., 479.

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1 引文斯高帕斯（Scopus）

Mycelial mattress from a sporangia formation-delayed mutant of Rhizopus stoloniferas wound healing-enhancing biomaterial

Chien, M. Y., Chen, L. C., Chen, Y. C., Sheu, M. T., Tsai, Y. C., Ho, H. O., Su, C. H. & Liu, D. Z., 8月 14 2015, 於: PLoS ONE. 10, 8, e0134090.

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6 引文斯高帕斯（Scopus）

Neurocytoprotective effects of aliphatic hydroxamates from lovastatin, a secondary metabolite from monascus -fermented red mold rice, in 6-hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells

Lin, C-M., Lin, Y. T., Lin, R. D., Huang, W-J. & Lee, M-H., 5月 20 2015, 於: ACS Chemical Neuroscience. 6, 5, p. 716-724 9 p.

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33 引文斯高帕斯（Scopus）

New whitening constituents from taiwan-native Pyracantha koidzumii: Structures and tyrosinase inhibitory analysis in human epidermalmelanocytes

Lin, R. D., Chen, M. C., Liu, Y. L., Lin, Y. T., Lu, M. K., Hsu, F-L. & Lee, M. H., 12月 2 2015, 於: International Journal of Molecular Sciences. 16, 12, p. 28598-28613 16 p.

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19 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., 3月 1 2015, 於: Molecules. 20, 3, p. 4516-4529 14 p.

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10 引文斯高帕斯（Scopus）

Novel injectable thermosensitive hydrogels for delivering hyaluronic acid-doxorubicin nanocomplexes to locally treat tumors

Jhan, H. J., Liu, J. J., Chen, Y. C., Liu, D. Z., Sheu, M. T. & Ho, H. O., 4月 1 2015, 於: Nanomedicine. 10, 8, p. 1263-1274 12 p.

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35 引文斯高帕斯（Scopus）

N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling

Lai, M-J., Lee, H. Y., Chuang, H-Y., Chang, L-H., Tsai, A-C., Chen, M. C., Huang, H-L., Wu, Y-W., Teng, C-M., Pan, S. L., Liu, Y-M., Mehndiratta, S. & Liou, J. P., 8月 27 2015, 於: Journal of Medicinal Chemistry. 58, 16, p. 6549-6558 10 p.

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27 引文斯高帕斯（Scopus）

Pb²⁺ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells

Chan, C. P., Tsai, Y. T., Chen, Y. L., Hsu, Y. W., Tseng, J. T., Chuang, H. Y., Shiurba, R., Lee, M. H., Wang, J. Y. & Chang, W. C., 2月 1 2015, 於: Environmental Toxicology. 30, 2, p. 129-136 8 p.

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7 引文斯高帕斯（Scopus）

Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles

Chen, Y. C., Su, C. Y., Jhan, H. J., Ho, H. O. & Sheu, M. T., 12月 2 2015, 於: International Journal of Nanomedicine. 10, p. 7265-7274 10 p.

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33 引文斯高帕斯（Scopus）

Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells

Wang, C-W., Wang, C. K., Chang, Y. J., Choong, C. Y., Lin, C. S., Tai, C. J. & Tai, C. J., 2015, 於: Evidence-based Complementary and Alternative Medicine. 2015, 570785.

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11 引文斯高帕斯（Scopus）

Pyrimidinedione-mediated selective histone deacetylase 6 inhibitors with antitumor activity in colorectal cancer HCT116 cells

Liu, Y-M., Lee, H. Y., Lai, M-J., Pan, S. L., Huang, H-L., Kuo, F-C., Chen, M. C. & Liou, J. P., 8月 17 2015, 於: Organic and Biomolecular Chemistry. 13, 40, p. 10226-10235 10 p.

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14 引文斯高帕斯（Scopus）

R173W mutation of hydroxymethylbilane synthetase is associated with acute intermittent porphyria complicated with rhabdomyolysis: The first report

Chen, M. C., Chang, C. J., Lu, Y. H., Niu, D. M., Lou, H. Y. & Chang, C. C., 3月 13 2015, 於: Journal of Clinical Gastroenterology. 49, 3, p. 256-257 2 p.

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6 引文斯高帕斯（Scopus）

Redox reaction mediated direct synthesis of hierarchical flower-like CuO spheres anchored on electrospun poly(vinylidene difluoride) fiber surfaces at low temperatures

Lee, Y. Y., Li, H. Y., Chiu, S. J., Liang, W. L., Yeh, P. L. & Liu, Y. L., 2015, 於: RSC Advances. 5, 121, p. 100228-100234 7 p.

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6 引文斯高帕斯（Scopus）

Selective delivery of PEGylated compounds to tumor cells by anti-PEG hybrid antibodies

Tung, H. Y., Su, Y. C., Chen, B. M., Burnouf, P. A., Huang, W. C., Chuang, K. H., Yan, Y. T., Cheng, T. L. & Roffler, S. R., 6月 1 2015, 於: Molecular Cancer Therapeutics. 14, 6, p. 1317-1326 10 p.

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31 引文斯高帕斯（Scopus）

Swelling/floating capability and drug release characterizations of gastroretentive drug delivery system based on a combination of hydroxyethyl cellulose and sodium carboxymethyl cellulose

Chen, Y. C., Ho, H. O., Liu, D. Z., Siow, W. S. & Sheu, M. T., 1月 24 2015, 於: PLoS ONE. 10, 1, e0116914.

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43 引文斯高帕斯（Scopus）

The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death

Huang, Y. H., Huang, S. W., Hsu, Y. F., Ou, G., Huang, W. J. & Hsu, M. J., 10月 29 2015, 於: Scientific Reports. 5, 15900.

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8 引文斯高帕斯（Scopus）

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells

Lin, L. T., Tai, C. J., Su, C-H., Chang, F. M., Choong, C. Y., Wang, C. K. & Tai, C. J., 2015, 於: BioMed Research International. 2015, 415269.

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12 引文斯高帕斯（Scopus）

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., 6月 1 2015, 於: Molecular Pharmacology. 87, 6, p. 996-1005 10 p.

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19 引文斯高帕斯（Scopus）

Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1

Chao, S. W., Su, M. Y., Chiou, L. C., Chen, L. C., Chang, C. I. & Huang, W. J., 8月 28 2015, 於: Journal of Natural Products. 78, 8, p. 1969-1976 8 p.

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24 引文斯高帕斯（Scopus）

Vitis thunbergii var. taiwaniana Extracts and Purified Compounds Ameliorate Obesity in High-Fat Diet-Induced Obese Mice

Lin, S. Y., Huang, G. C., Hsieh, Y. Y., Lin, Y. S., Han, C. H., Wen, C. L., Chang, C. I. & Hou, W. C., 10月 28 2015, 於: Journal of Agricultural and Food Chemistry. 63, 42, p. 9286-9294 9 p.

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8 引文斯高帕斯（Scopus）

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domaincontaining protein tyrosine phosphatase 1

Chang, Y. F., Hsu, Y. F., Chiu, P. T., Huang, W. J., Huang, S. W., Ou, G., Sheu, J. R. & Hsu, M. J., 2015, 於: Oncotarget. 6, 1, p. 85-100 16 p.

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12 引文斯高帕斯（Scopus）

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-inflammatory properties via MKP-1 in LPS-stimulated RAW264.7 macrophages

Chen, W. C., Yen, C. S., Huang, W. J., Hsu, Y. F., Ou, G. & Hsu, M. J., 4月 2015, 於: British Journal of Pharmacology. 172, 7, p. 1894-1908 15 p.

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23 引文斯高帕斯（Scopus）

Women who conceived with infertility treatment were more likely to receive planned cesarean deliveries in Taiwan

Chien, L. Y., Lee, Y. H., Lin, Y. H. & Tai, C. J., 6月 1 2015, 於: Human Fertility. 18, 2, p. 141-148 8 p.

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5 引文斯高帕斯（Scopus）

Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice

Shieh, Y. H., Huang, H. M., Wang, C. C., Lee, C. C., Fan, C. K. & Lee, Y. L., 2月 2015, 於: International Immunopharmacology. 24, 2, p. 383-391 9 p.

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51 引文斯高帕斯（Scopus）

不孕症夫妻同治病例分享

YuChuan, C. & Chen-Jei, T., 2015, 於: 中醫婦科醫學雜誌. 19, p. 37-41 5 p.

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