CRISPR基因編輯核心實驗室

2023

A low-molecular-weight chitosan fluorometric-based assay for evaluating antiangiogenic drugs

Wang, C. Y., Chou, C. M., Chu, C. Y., Chen, A., Liu, E. H., Liu, C. Y., Lee, Y. L. A., Mi, F. L. & Cheng, C. H., 1月 2023, 於: International Journal of Biological Macromolecules. 224, p. 927-937 11 p.

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2022

The ADAM9/UBN2/AKR1C3 axis promotes resistance to androgen-deprivation in prostate cancer

Le, T. T-H., Hsieh, C-L., Lin, I-H., Chu, C-Y., Do, A. D., Chen, S-H., Shigemura, K., Kitagawa, K., Fujisawa, M., Liu, M-C., Chen, K-C. & Sung, S-Y., 2022, 於: American Journal of Cancer Research. 12, 1, p. 176-197 22 p.

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2021

Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells

Chen, C. L., Hsu, S. C., Chung, T. Y., Chu, C. Y., Wang, H. J., Hsiao, P. W., Yeh, S. D., Ann, D. K., Yen, Y. & Kung, H. J., 12月 2021, 於: Nature Communications. 12, 1, 2398.

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43 引文斯高帕斯（Scopus）

Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes

Hsu, S. C., Chen, C. L., Cheng, M. L., Chu, C. Y., Changou, C. A., Yu, Y. L., Yeh, S. D., Kuo, T. C., Kuo, C. C., Chuu, C. P., Li, C. F., Wang, L. H., Chen, H. W., Yen, Y., Ann, D. K., Wang, H. J. & Kung, H. J., 2021, 於: Theranostics. 11, 15, p. 7527-7545 19 p.

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18 引文斯高帕斯（Scopus）

Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein

Cheng, T. C., Sayseng, J. O., Tu, S. H., Juan, T. C., Fang, C. L., Liao, Y. C., Chu, C. Y., Chang, H. W., Yen, Y., Chen, L. C. & Ho, Y. S., 2021, 於: Journal of Food and Drug Analysis. 29, 4, p. 622-637 16 p., 6.

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8 引文斯高帕斯（Scopus）

Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy

Chu, C. Y., Lee, Y. C., Hsieh, C. H., Yeh, C. T., Chao, T. Y., Chen, P. H., Lin, I. H., Hsieh, T. H., Shih, J. W., Cheng, C. H., Chang, C. C., Lin, P. S., Huang, Y. L., Chen, T. M., Yen, Y., Ann, D. K. & Kung, H. J., 2021, 於: Theranostics. 11, 8, p. 3624-3641 18 p.

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10 引文斯高帕斯（Scopus）

2020

Characterization and toxicology evaluation of low molecular weight chitosan on zebrafish

Chou, C. M., Mi, F. L., Horng, J. L., Lin, L. Y., Tsai, M. L., Liu, C. L., Lu, K. Y., Chu, C. Y., Chen, Y. T., Lee, Y. L. A. & Cheng, C. H., 7月 15 2020, 於: Carbohydrate Polymers. 240, 1 p., 116164.

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13 引文斯高帕斯（Scopus）

Tesc promotes tgf-ᾳ/egfr-foxm1-mediated tumor progression in cholangiocarcinoma

Hsieh, C. H., Chu, C. Y., Lin, S. E., Yang, Y. C. S. H., Chang, H. S. & Yen, Y., 5月 2020, 於: Cancers. 12, 5, 1105.

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8 引文斯高帕斯（Scopus）

2019

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P., 及其他3Wang, W. C., Chen, H. W. & Kung, H. J., 1月 3 2019, 於: Oncogene. 38, 1, p. 17-32 16 p.

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71 引文斯高帕斯（Scopus）

Metastatic colorectal cancer rewrites metabolic program through a Glut3-YAP-dependent signaling circuit

Kuo, C. C., Ling, H. H., Chiang, M. C., Chung, C. H., Lee, W. Y., Chu, C. Y., Wu, Y. C., Chen, C. H., Lai, Y. W., Tsai, I. L., Cheng, C. H. & Lin, C. W., 1月 1 2019, 於: Theranostics. 9, 9, p. 2526-2540 15 p.

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55 引文斯高帕斯（Scopus）

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

Fan, J. J., Hsu, W. H., Hung, H. H., Zhang, W. J., A Lee, Y. L., Chen, K. C., Chu, C. Y., Ko, T. P., Lee, M. T., Lin, C. W. & Cheng, C. H., 5月 2019, 於: International Journal of Oncology. 54, 5, p. 1639-1650 12 p.

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11 引文斯高帕斯（Scopus）

2018

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., 3月 1 2018, 於: Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

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38 引文斯高帕斯（Scopus）

Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

Chen, K. C., Hsu, W. H., Ho, J. Y., Lin, C. W., Chu, C. Y., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., 7月 2018, 於: Journal of Food and Drug Analysis. 26, 3, p. 1180-1191 12 p.

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49 引文斯高帕斯（Scopus）

2017

IRF9-Stat2 Fusion Protein as an Innate Immune Inducer to Activate Mx and Interferon-Stimulated Gene Expression in Zebrafish Larvae

Huang, C. J., Chou, C. M., Lien, H. W., Chu, C. Y., Ho, J. Y., Wu, Y. & Cheng, C. H., 6月 1 2017, 於: Marine Biotechnology. 19, 3, p. 310-319 10 p.

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9 引文斯高帕斯（Scopus）

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Shih, J. W., Chiang, W. F., Wu, A. T. H., Wu, M. H., Wang, L. Y., Yu, Y. L., Hung, Y. W., Wang, W. C., Chu, C. Y., Hung, C. L., Changou, C. A., Yen, Y. & Kung, H. J., 6月 22 2017, 於: Nature Communications. 8, 15874.

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148 引文斯高帕斯（Scopus）

Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

Chen, P. C., Tang, C. H., Lin, L. W., Tsai, C. H., Chu, C. Y., Lin, T. H. & Huang, Y. L., 1月 25 2017, 於: Journal of Hematology and Oncology. 10, 1, 33.

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61 引文斯高帕斯（Scopus）

2016

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Lin, T. P., Chang, Y. T., Lee, S. Y., Campbell, M., Wang, T. C., Shen, S. H., Chung, H. J., Chang, Y. H., Chiu, A. W., Pan, C. C., Lin, C. H., Chu, C. Y., Kung, H. J., Cheng, C. Y. & Chang, P. C., 5月 1 2016, 於: Oncotarget. 7, 18, p. 26137-26151 15 p.

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42 引文斯高帕斯（Scopus）

2014

Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells

Chang, P. C., Wang, T. Y., Chang, Y. T., Chu, C. Y., Lee, C. L., Hsu, H. W., Zhou, T. A., Wu, Z., Kim, R. H., Desai, S. J., Liu, S. & Kung, H. J., 2月 14 2014, 於: PLoS One. 9, 2, e88556.

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51 引文斯高帕斯（Scopus）

Cancer: Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells

Qiu, F., Chen, Y. R., Liu, X., Chu, C. Y., Shen, L. J., Xu, J., Gaur, S., Forman, H. J., Zhang, H., Zheng, S., Yen, Y., Huang, J., Kung, H. J. & Ann, D. K., 4月 1 2014, 於: Science Signaling. 7, 319, p. ra31

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130 引文斯高帕斯（Scopus）

Differential regulation of Tetraodon nigroviridis Mx gene promoter activity by constitutively-active forms of STAT1, STAT2, and IRF9

Cheng, C. H., Chou, C. M., Chu, C. Y., Chen, G. D., Lien, H. W., Hwang, P. P., Chang, M. S. & Huang, C. J., 5月 2014, 於: Fish and Shellfish Immunology. 38, 1, p. 230-243 14 p.

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21 引文斯高帕斯（Scopus）

2010

Expression and characterization of a constitutively active STAT6 from Tetraodon

Sung, S. C., Cheng, C. H., Chou, C. M., Chu, C. Y., Chen, G. D., Hwang, P. P., Huang, F. L. & Huang, C. J., 2010, 於: Fish and Shellfish Immunology. 28, 5-6, p. 819-828 10 p.

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10 引文斯高帕斯（Scopus）

2008

Expression and characterization of two STAT isoforms from Sf9 cells

Yeh, M. S., Cheng, C. H., Chou, C. M., Hsu, Y. L., Chu, C. Y., Chen, G. D., Chen, S. T., Chen, G. C. & Huang, C. J., 2008, 於: Developmental and Comparative Immunology. 32, 7, p. 814-824 11 p.

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12 引文斯高帕斯（Scopus）

CRISPR基因編輯核心實驗室

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