藥學院

2025

2-Hydroxyl hispolon reverses high glucose-induced endothelial progenitor cell dysfunction through the PI3K/Akt/eNOS and AMPK/HO-1 pathways

Wang, T. J., Hou, W. C., Hsiao, B. Y., Lo, T. H., Chen, Y. T., Yang, C. H., Shih, Y. T. & Liu, J. C., 2025, (接受/付印) 於: British Journal of Pharmacology.

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Activation of the Trichodimerol Pathway through Deletion of mcrA in Marine Penicillium rubens YAP001

Shyong, J., Tran Huynh, Q. D., Dziedzic, S., Aguirre, E., Rabot, C., Yuan, B., Herrero-MacKenzie, H. E., Stajich, J. E., Lee, C. K., Kenkel, C. D. & Wang, C. C. C., 2025, (接受/付印) 於: ACS Chemical Biology. 20, 4, p. 823-829 7 p.

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Acute myocardial infarction risk prediction in emergency chest pain patients: An external validation study

Chang, C. H., Nguyen, P. A., Huang, C. C., Liu, C. F., Melisa, S., Chen, C. J., Hsu, C. C., Lin, H. J., Hsu, M. H., Shih, C. M., Liu, J. C., Yang, H. Y. & Hsu, J. C., 1月 2025, 於: International Journal of Medical Informatics. 193, 105683.

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1 引文斯高帕斯（Scopus）

Advancing glioblastoma therapy: Learning from the past and innovations for the future

Rana, M., Liou, K. C., Thakur, A., Nepali, K. & Liou, J. P., 5月 1 2025, 於: Cancer Letters. 617, 217601.

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Anti-inflammatory and Hepatoprotective Iridoid Glycosides from the Roots of Gomphandra mollis

Tran Huynh, Q. D., Phan, T. T. T., Liu, T. W., Nguyen, T. V., Duong, T. L. T., Hsu, S. J., Chu, M. H., Wang, Y. H., Nguyen Bui, B. T., Nguyen, D. K., Vo, T. H. & Lee, C. K., 2025, (接受/付印) 於: Journal of Natural Products.

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Areca catechu L. Extract Inhibits Colorectal Cancer Tumor Growth by Modulating Cell Apoptosis and Autophagy

Tsai, M. H., Chen, C. H., Chen, C. L., Lee, M. H., Wu, L. C., Hsu, Y. C., Hsiao, C. Y., Lee, C. T., Pi, K. L. & Su, L. J., 2月 2025, 於: Current Issues in Molecular Biology. 47, 2, 128.

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Artificial intelligence for predicting interstitial fibrosis and tubular atrophy using diagnostic ultrasound imaging and biomarkers

Chang, T. W., Tsai, C. Y., Tang, Z. Y., Zheng, C. M., Liao, C. T., Cheng, C. Y., Wu, M. S., Shen, C. C. & Lin, Y. C., 3月 17 2025, 於: BMJ Health and Care Informatics. 32, 1, e101192.

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A sensitive post-column derivatization approach for enhancing hydroxyl metabolites detection

Lin, Y. C., Huang, S. W., Wang, S. Y., Su, J. R., Wang, J. J., Hsu, M. J. & Liao, H. W., 2月 1 2025, 於: Analytica Chimica Acta. 1337, p. 343559 343559.

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1 引文斯高帕斯（Scopus）

Aspartame consumption linked to delayed puberty and mitochondrial Dysfunction: Evidence from human and animal studies

Chen, Y. C., Wang, Z. L., Lin, Y. F., Lin, C. Y., Hsu, S. Y., Nacis, J. S. & Hsieh, R. H., 6月 2025, 於: Journal of Nutritional Biochemistry. 140, 109889.

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Aspirin after completion of standard adjuvant therapy for colorectal cancer (ASCOLT): an international, multicentre, phase 3, randomised, double-blind, placebo-controlled trial

Chia, J. W. K., Segelov, E., Deng, Y., Ho, G. F., Wang, W., Han, S., Sharma, A., Ding, K., Chen, G., Jeffery, M. G., Tham, C. K., Ahn, J. B., Nott, L., Zielinski, R., Chao, T.-Y., van Hagen, T., Wei, P.-L., Day, F., Mehta, S. & Yau, T. 及其他10, Peng, J., Hayes, T. M., Li, Y., Gandhi, M., Foo, E. M. J., Rahman, N., Rothwell, P., Ali, R., Simes, J. & Toh, H. C., 3月 2025, 於: The Lancet Gastroenterology and Hepatology. 10, 3, p. 198-209 12 p.

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1 引文斯高帕斯（Scopus）

Assessing therapeutic efficacy of Chlorella vulgaris peptides on pathogenic bacteria associated with periodontal disease

Wang, S. M., Chang, C. Y., Chuu, J. J. & Lee, C. K., 2025, 於: CYTA - Journal of Food. 23, 1, 2471783.

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Association Between Current Medical Decision-Making Participation Self-Efficacy and Advance Care Planning Engagement Among Older Adults: Baseline Findings from a Nationwide Longitudinal Cohort Study

Lin, C. P., Liao, J. Y., Huang, C. H., Cheng, S. Y., Tseng, W. Z., Mori, M., Chang, H. C., Li, C. M., Sun, W. J., Wu, C. Y., Chiou, H. Y., Yu, S. J., Hsiung, C. A. & Chen, P. J., 1月 1 2025, 於: Journal of Palliative Medicine. 28, 1, p. 50-58 9 p.

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1 引文斯高帕斯（Scopus）

Association Between Short-term Ambient Air Pollution and Psoriasis: A Time-Stratified Case-Crossover Study

Chen, Y. T., Li, Y. L., Wu, C. Y., Chen, L. Y. & Chiou, H. Y., 2025, 於: Asia-Pacific Journal of Public Health.

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Association of long-term ozone exposure with the incidence and progression of hypertension, diabetes, and chronic kidney disease: A national retrospective cohort study

Li, Y. L., Chang, P. Y., Chuang, T. W., Hsieh, Y. C., Wang, B. S., Chen, S. Y. & Chiou, H. Y., 5月 1 2025, 於: Science of the Total Environment. 975, 179209.

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Associations between paraoxonase-1 activity and therapeutic drug monitoring indicators in schizophrenia patients treated with olanzapine: A cross-sectional study

Wu, T. H., Hu, S. C., Sylfa, N., Liao, J. H., Raza, A., Chen, B. L., Chen, C. H. & Lu, M. L., 2025, (接受/付印) 於: Journal of Psychopharmacology. 39, 2, p. 141-146 6 p.

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Atrasentan in Patients with IgA Nephropathy

ALIGN Study Investigators & Wu, M.-S., 2月 6 2025, 於: The New England journal of medicine. 392, 6, p. 544-554 11 p.

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14 引文斯高帕斯（Scopus）

Automatic Movement Recognition for Evaluating the Gross Motor Development of Infants

Yang, Y. Z., Tsai, J. A., Yu, Y. L., Ko, M. H. J., Chiou, H. Y., Pai, T. W. & Chen, H. J., 3月 2025, 於: Children. 12, 3, 310.

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Bioprospection of Hura crepitans metabolites against oxidative stress and inflammation: An in vitro and in silico exploration

Kuo, Y. C., Lawal, B., Lukman, H. Y., Chen, L. C., Huang, S. L., Chen, Y. F., Fadaka, A. O., Olawale, F., Olasupo, A., Ajenifujah, O. T., Fouad, D., Papadakis, M., Batiha, G. E. S., Sabiu, S., Wu, A. T. H. & Huang, H. S., 2025, 於: International Journal of Medical Sciences. 22, 8, p. 1837-1851 15 p.

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Characteristics and hospitalization of people living with dementia after home healthcare: A nationwide cohort study

Wang, Y. C., Tsai, K. T., Ho, C. H., Tseng, W. Z., Petersen, I., Lai, Y. C., Chiou, H. Y., Hsiung, C. A., Yu, S. J., Sampson, E. L., Liao, J. Y. & Chen, P. J., 1月 3 2025, 於: Medicine (United States). 104, 1, p. e40981

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Chemical constituents from marine medicinal brown alga-derived Scytalidium lignicola SC228

Hsi, H. Y., Hsiao, G., Wang, S. W., Huang, S. J. & Lee, T. H., 1月 2025, 於: Phytochemistry. 229, 114289.

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1 引文斯高帕斯（Scopus）

CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma

Lee, K. L., Liu, J. J., Huang, W. J., Hung, C. S. & Liang, Y. C., 12月 2025, 於: Cancer Cell International. 25, 1, 56.

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Cogstate Brief Battery performance in assessing cognitive impairment in Taiwan: A prospective, multi-center study

Kuan, Y. C., Jhang, K. M., Wang, W. F., Yeh, Y. C., Chen, C. S., Yang, C. C. & Hu, C. J., 2025, 於: Journal of the Formosan Medical Association.

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Comparison of global transcriptomes for nontyphoidal Salmonella clinical isolates from pediatric patients with and without bacteremia after their interaction with human intestinal epithelial cells in vitro

Batsaikhan, B., Lin, P. C., Shigemura, K., Wu, Y. W., Onishi, R., Chang, P. R., Cheng, H. Y. & Fang, S. B., 2月 2025, 於: Journal of Microbiology, Immunology and Infection. 58, 1, p. 38-47 10 p.

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Cytotoxicity-guided isolation of elatostemanosides I-VI from Elatostema tenuicaudatum W. T. Wang and their cytotoxic activities

Huynh, Q. D. T., Phan, T. T. T., Liu, T. W., Duong, T. L. T., Hsu, S. J., Kuo, C. C., Chu, M. H., Wang, Y. H., Nguyen, T. V., Shen, Y. A., Fan, Y. J., Nguyen, D. K., Vo, T. H. & Lee, C. K., 4月 4 2025, 於: RSC Advances. 15, 14, p. 10639-10652 14 p.

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Design, preparation, and characterization of injectable thermosensitive polymer-based hydrogels with enhanced mechanical properties for sustained liraglutide release

Cheng, W. J., Yeh, T. Y., Hsieh, C. Y., Chuang, H. Y., Chao, F. C., Liou, J. P. & Hsieh, C. M., 6月 2025, 於: Journal of Drug Delivery Science and Technology. 108, 106909.

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Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection

Banerjee, S., Hsu, Y. T., Nguyen, D. H., Yeh, S. H., Liou, K. C., Liu, J. J., Liou, J. P. & Chuang, J. Y., 2月 2025, 於: Biomedicine and Pharmacotherapy. 183, 117851.

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Diagnostic performance of rapid on-site evaluation during bronchoscopy for lung cancer: A comprehensive meta-analysis

Chen, C. C., Lu, S. C., Chang, Y. K., Bai, C. H., Hsiao, K. Y., Lee, K. Y. & Wang, Y. H., 1月 2025, 於: Cancer cytopathology. 133, 1, e22908.

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Discoidin domain receptor inhibitor DDR1-IN-1 induces autophagy and necroptotic cell death in malignant peripheral nerve sheath tumor

Lai, G. Y., Lee, Y. C., Weng, H. J., Lai, K. H., Hsiang, M. C., Hsu, K. Y. & Liao, C. P., 12月 2025, 於: Cell Death Discovery. 11, 1, 83.

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Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase

Chu, J. C., Tsai, K. C., Wang, T. Y., Chen, T. Y., Tsai, J. Y., Lee, T., Lin, M. H., Hsieh, Y. S. Y., Wu, C. C. & Huang, W. J., 2月 5 2025, 於: European Journal of Medicinal Chemistry. 283, p. 117169 117169.

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1 引文斯高帕斯（Scopus）

Disrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize

Quetzal, T. M., Lo, W. C., Chiu, Y. W. & Chiou, H. Y., 1月 24 2025, 於: Scientific Reports. 15, 1, p. 3017 1 p., 3017.

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Do phenolic contents relate to their in-vitro cytotoxicity against colorectal cancer cell lines from Calvatia lilacina (puffball mushroom)?

Cao, J. L., Guo, J. H., Leung, W., Liu, Y. T., Tsai, I. L., Huang, S. L., Wang, Y. S. & Lai, Y. H., 4月 2025, 於: Food Bioscience. 66, 106193.

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Dynamic changes in the metabolome and microbiome during Citrus depressa Hayata liquid fermentation

Liu, T. W., Iskandar, B., Chu, M. H., Wang, Y. H., Huang, T. A., Hsu, S. J., Hsieh, Y. S. Y. & Lee, C. K., 1月 15 2025, 於: Food Chemistry. 463, 141225.

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Early-Life Risks of Central Precocious Puberty

Yin, W. J., Hsu, J. W., Chen, C. C., Su, E. C. Y., Wang, S. Y., Chen, Y. J. & Chen, Y. C., 2025, (接受/付印) 於: Endocrine Practice.

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Early prediction of cardiovascular events following treatments in female breast cancer patients: Application of real-world data and artificial intelligence

Nguyen, Q. T. N., Lin, S. J., Nguyen, P. A., Phuc, P. T., Hsu, M. H., Huang, C. Y., Hung, C. S., Lu, C. Y. & Hsu, J. C., 6月 2025, 於: Breast. 81, 104438.

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Effectiveness of pudendal nerve block in the management of acute post-haemorrhoidectomy pain in Asian individuals using inverse probability of treatment weighting (IPTW)

Chen, C. C., Chang, K. T., Lee, Y. W., Chen, J. S., Wei, P. L., Chang, C. L. & Huang, Y. J., 1月 2025, 於: Asian Journal of Surgery. 48, 1, p. 131-136 6 p.

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Efficacy and Safety of Ravulizumab in IgA Nephropathy: A Phase 2 Randomized Double-Blind Placebo-Controlled Trial

The SANCTUARY Study Investigators, 4月 2025, 於: Journal of the American Society of Nephrology. 36, 4, p. 645-656 12 p., 10.1681/ASN.0000000534.

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6 引文斯高帕斯（Scopus）

Enhanced CXCL10 expression in mast cells for cutaneous neurofibroma presenting with pain and itch: Cellular and Molecular Biology

Pham, T. T. Q., Liao, C. P., Shih, Y. H., Lee, W. R., Liao, Y. H., Chou, C. L., Chiu, Y. W., Liu, D., Wang, H. C., Chen, B. J., Shao, Y. H. J., Yeh, T. S., Lai, K. H. & Weng, H. J., 2025, (接受/付印) 於: British Journal of Cancer. 132, 7, p. 611-621 11 p., 774.

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Epigenetic Modifications as Novel Therapeutic Strategies of Cancer Chemoprevention by Phytochemicals

Hsieh, H. H., Kuo, M. Z., Chen, I. A., Lin, C. J., Hsu, V., HuangFu, W. C. & Wu, T. Y., 2025, (接受/付印) 於: Pharmaceutical Research. 42, 1, p. 69-78 10 p., 111502.

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Exploring Mortality and Prognostic Factors of Heart Failure with In-Hospital and Emergency Patients by Electronic Medical Records: A Machine Learning Approach

Yu, C. S., Lwu, J., Shih, C. M., Chiu, K. L., Chen, Y. D. & Chang, T. H., 2025, 於: Risk Management and Healthcare Policy. 18, p. 77-93 17 p.

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1 引文斯高帕斯（Scopus）

Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities

Lau, P. P., Wei, C. Y., Lin, M. R., Chou, W. H., Wan, Y. J. Y. & Chang, W. C., 12月 2025, 於: Cell and Bioscience. 15, 1, 19.

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Guizhi Fuling Wan ameliorates concanavalin A-induced autoimmune hepatitis in mice

Kuo, S. L., Su, C. H., Lai, K. H., Chang, Y. C., You, J. S., Peng, H. H., Chen, C. H., Lin, C. C., Chen, P. J. & Hwang, T. L., 2月 2025, 於: Biomedical Journal. 48, 1, 100731.

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2 引文斯高帕斯（Scopus）

Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Cheng, T.-C., Hung, M.-C., Wang, L.-H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C.-L., Whang-Peng, J., Lee, W.-J., Liao, Y.-C., Lee, Y.-C., Pan, M.-H., Lin, H.-K., Tzeng, H.-E., Guo, P., Chu, C.-Y. & Chen, L.-C., 1月 9 2025, 於: Biomarker Research. 13, 1, p. 7

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Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Cheng, T. C., Hung, M. C., Wang, L. H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C. L., Whang-Peng, J., Lee, W. J., Liao, Y. C., Lee, Y.-C., Pan, M. H., Lin, H. K., Tzeng, H.-E., Guo, P., Chu, C.-Y., Chen, L. C. & Ho, Y.-S., 12月 2025, 於: Biomarker Research. 13, 1, 7.

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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening

Yang, C. L., Wu, Y. W., Tu, H. J., Yeh, Y. H., Lin, T. E., Sung, T. Y., Li, M. C., Yen, S. C., Hsieh, J. H., Yu, M. C., Hsieh, S. Y., Hsieh, H. P., Pan, S. L. & Hsu, K. C., 2025, (接受/付印) 於: Advanced Science.

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Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening

Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., 1月 13 2025, 於: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.

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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment

Lee, G. A., Hsu, J. B. K., Chang, Y. W., Hsieh, L. C., Li, Y. T., Wu, Y. C., Chu, C. Y., Chiang, Y. H., Guo, W. Y., Wu, C. C., Chen, L. W., Kao, H. W., Lin, W. L., Tseng, L., Weng, T. W., Kuo, D. P., Cheng, S. J., Chen, Y. C., Huang, S. W. & Kung, H. J. 及其他1, Chen, C. Y., 3月 8 2025, 於: Journal of Biomedical Science. 32, 1, p. 34 34.

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Impact of an interactive dietary management program on nephrolithiasis patients in Taiwan

Khaleel, A., Wei, P. H., Tu, C., Chuang, Y. T., Kuo, L. N. & Chen, H. Y., 12月 2025, 於: Discover Food. 5, 1, 86.

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Impact of PM_2.5, relative humidity, and temperature on sleep quality: a cross-sectional study in Taipei

Thanh Tung, N., Lee, Y. L., Liu, W. T., Lin, Y. C., Chang, J. H., Xuan Thao, H. N., Ba Dung, H., Viet Trung, L., Phan Chung Thuy, T., Thi Hien, N., Tsai, C. Y., Lo, C. C., Lo, K., Ho, K. F., Chuang, K. J. & Chuang, H. C., 2025, 於: Annals of Medicine. 57, 1, 2448733.

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Increased risk of breast cancer among premenopausal women with pituitary gland disorders in Taiwan: a population-based matched-cohort study

Lin, C. C., Lin, C. J., Hsieh, Y. C., Lin, J. H., Tsai, H. Y., Wu, C. Y. & Chiou, H. Y., 3月 2025, 於: Journal of Endocrinological Investigation. 48, 3, p. 681-689 9 p.

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Insights into the structural diversity of cembranoids from Sarcophyton glaucum and their bioactivity

Lai, K. H., Chung, H. L., Chen, Y. Y., Zheng, L. G., Su, J. H. & El-Shazly, M., 2月 12 2025, 於: RSC Advances. 15, 6, p. 4702-4707 6 p.

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