The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair

Bingsen Zhou (Contributor)
Keqiang Zhang (Contributor)
F. Un (Contributor)
Shuya Hu (Contributor)
Jun Wu (Contributor)
Yan Wang (Contributor)
Xiyong Liu (Contributor)
Hongzhi Li (Contributor)
Zheng Liu (Contributor)
Leila Su (Contributor)
Yun Yen (Contributor)

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Description

Mechanism of Action Study for COH29 Compare COH29 treatment in DNA-repair deficient cell line with truncated BRCA1 (HCC1937) versus phenotypically normal cell line with exogenous WT BRCA1 expression (HCC1937+BRCA1)

可用日期	2015
發行者	ArrayExpress

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https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55004

1 文章

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros
Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., 6月 1 2015, 於: Molecular Pharmacology. 87, 6, p. 996-1005 10 p.
研究成果: 雜誌貢獻 › 文章 › 同行評審

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21 引文斯高帕斯（Scopus）

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Zhou, B. (Contributor), Zhang, K. (Contributor), Un, F. (Contributor), Hu, S. (Contributor), Wu, J. (Contributor), Wang, Y. (Contributor), Liu, X. (Contributor), Li, H. (Contributor), Liu, Z. (Contributor), Su, L. (Contributor), Yen, Y. (Contributor) (2015). The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair. ArrayExpress.

The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair

Description

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研究成果

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

引用此