Effect of particle morphology on performance of an electrostatic air–liquid interface cell exposure system for nanotoxicology studies

  • Li-Ti Chou (Contributor)
  • Ta Chih Hsiao (Contributor)
  • Tsun Jen Cheng (Contributor)
  • Hsiao-Chi Chuang (Contributor)
  • Jing Chi Lin (Contributor)



Particle morphology can affect the performance of an electrostatic precipitator air–liquid interface (ESP-ALI) cell exposure system and the resulting cell toxicity. In this study, three types of monodisperse aerosols – spherical sucrose particles, nonspherical align soot aggregates, and nanosilver aggregates/agglomerates – were selected to evaluate the collection efficiency at flow rates ranging from 0.3 to 1.5 lpm. To quantify the particle morphology, the fractal dimensions (<i>D<sub>f</sub></i>) of the tested aerosols were characterized. The penetration of fine particles (<i>d<sub>p</sub></i> = 100–250<b> </b>nm) under different operating conditions was correlated with a characteristic exponential curve using the dimensionless drift velocity (<i>V<sub>c</sub>/V<sub>avg,r</sub></i>) as the scaling parameter. For nanoparticles (NPs, <i>d<sub>p</sub></i> &lt;100<b> </b>nm) with different particle morphologies, the particle penetrations in the ESP-ALI were similar, but their diffusion losses were not negligible. In contrast, for fine particles, the collection efficiency of soot nanoaggregates (<i>D<sub>f</sub></i> = 2.29) was higher than that of spherical sucrose particles. This difference might be due to the simultaneous influences of the electric field-induced and flow field-induced alignment. Furthermore, based on Zhibin and Guoquan’s Deutsch model, a quadratic equation was applied to fit the experimental data and to predict the performance of the ESP-ALI.
發行者Taylor & Francis