Additional file 2: of Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer

Figure S2. Effects of SDCSC-exosomes on hematopoietic stem cells, progenitors and neutrophils. (A) The flow cytometry results for showing gating strategies for mouse hematopoietic stem cells and progenitors. LSK cells, lineage(-)ScaI(+)Kit(+) hematopoietic stem cells; LK, lineage(-)Kit(+) progenitors; GMPs, granulocyte-macrophage progenitors; CMPs, common myeloid progenitors; MEPs, megakaryocyte-erythroid progenitors, Lin, lineage marker. (B) Percentage of LSK, GMPs, CMPs and MEPs in bone marrows of mice injected with PBS (N=4) or CT26-SDCSC-exosomes (N=5). A total of 45 μg exosomes were injected. Data represent the mean ±S.D. (C) Percentage of neutrophils in spleens of mice injected with PBS (N=4) and CT26-SDCSC-exosomes (N=5). A total of 45 μg of SDCSC-exosomes were injected through tail vein. Data represent the mean ± SEM. (PDF 295 kb)