Abstract
This study was to evaluate the influence of masseter muscle on craniofacial growth and development by injection of botulinum neurotoxin to produce masseter muscle atrophy. Ten male Wstar rats (30 days old) received botulinum neurotoxin injection in one side of masseter muscle and normal saline n the other side; another three rats received no injection and serve as control group. All rats were sacrificed at 75 days of age. The masseter muscle were dissected and weighted and the anthropometric measurements were made directly on rat dry skulls. The results showed that the masseter muscle and muscle fiber cross-section area with botulinum neurotoxin injection was significantly smaller than that without injection. The craniofacial structures directly attached by masseter muscle were significantly smaller on the side with botulinum neurotoxin injection than that with normal saline injection. Our study suggested that atrophy of masseter muscle altered the craniofacial growth and development.
| Translated title of the contribution | The Influence of Masseter Muscle on Craniofacial Growth and Development-The Observation of Botulinum Neurotoxin Injection into the Masseter Muscle |
|---|---|
| Original language | Chinese (Traditional) |
| Pages (from-to) | 12-19 |
| Number of pages | 8 |
| Journal | 中華民國齒顎矯正學雜誌 |
| Volume | 18 |
| Issue number | 2 |
| Publication status | Published - 2006 |
Keywords
- botulinum neurotoxin
- masseter muscle
- muscle atrophy
- craniofacial bone
- growth and development