Zinc deficiency with acrodermatitis enteropathica-like eruption after pancreaticoduodenectomy

Hsin Hsien Yu, Yan Shen Shan, Pin Wen Lin

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Pancreaticoduodenectomy (PD) is the standard operation for periampullary lesions. Most reports have focused on the clinical outcome, complications and tumor recurrence after PD. Few studies have focused on the nutritional sequelae that result from the extended resection of the upper gastrointestinal tract and disruption of the normal physiologic process of digestion. Zinc is absorbed mainly in the duodenum and proximal jejunum, which are removed during PD. Herein, we report two patients who experienced zinc deficiency with acrodermatitis enteropathica-like eruption, alopecia, glossitis and nail dystrophy after PD. The lesions improved dramatically after supplementation with zinc sulfate, pancreatic enzyme and diet instructions. No symptoms related to zinc deficiency were noted on follow-up after nutritional instructions had been given to the patients.

Original languageEnglish
Pages (from-to)864-868
Number of pages5
JournalJournal of the Formosan Medical Association
Issue number10
Publication statusPublished - Jan 1 2007
Externally publishedYes


  • Acrodermatitis enteropathica
  • Pancreaticoduodenectomy
  • Zinc deficiency

ASJC Scopus subject areas

  • Medicine(all)


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