WCN24-313 Improvement on disease interception for chronic kidney disease by manipulation of the intestinal microbiota in a mouse model

Introduction
The development of chronic kidney disease (CKD) and its progression to end-stage renal disease (ESRD), have been a major source of reduced quality of life and significant premature mortality. Previously, we have identified that levels of specific microbial species were significantly altered across early to advanced stages of CKD.