Warfarin-induced leukocytoclastic vasculitis: A case report and review of literature

Chien Yi Hsu; Wei Sheng Chen; Shih Hsien Sung

doi:10.2169/internalmedicine.51.6240

Warfarin-induced leukocytoclastic vasculitis: A case report and review of literature

Chien Yi Hsu, Wei Sheng Chen, Shih Hsien Sung

Research output: Contribution to journal › Review article › peer-review

18 Citations (Scopus)

Abstract

Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.

Original language	English
Pages (from-to)	601-606
Number of pages	6
Journal	Internal Medicine
Volume	51
Issue number	6
DOIs	https://doi.org/10.2169/internalmedicine.51.6240
Publication status	Published - Mar 20 2012
Externally published	Yes

Keywords

Leukocytoclastic vasculitis
Warfarin

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.51.6240

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title = "Warfarin-induced leukocytoclastic vasculitis: A case report and review of literature",

abstract = "Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.",

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T2 - A case report and review of literature

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AU - Chen, Wei Sheng

AU - Sung, Shih Hsien

PY - 2012/3/20

Y1 - 2012/3/20

N2 - Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.

AB - Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.

KW - Leukocytoclastic vasculitis

KW - Warfarin

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JO - Internal Medicine

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Warfarin-induced leukocytoclastic vasculitis: A case report and review of literature

Abstract

Keywords

ASJC Scopus subject areas

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