TY - JOUR
T1 - Vitamin D insufficiency and frailty syndrome in older adults living in a Northern Taiwan community
AU - Chang, Ching I.
AU - Chan, Ding Cheng (Derrick)
AU - Kuo, Ken N.
AU - Hsiung, Chao Agnes
AU - Chen, Ching Yu
N1 - Funding Information:
This study was supported by the 97_HDSP08_020 grant “Interventional study of Geriatric Frailty, Osteoporosis, and Depression in a Community Based Randomized Trial” from the National Health Research Institutes, Zhunan, Taiwan .
Publisher Copyright:
© 2010 Elsevier Ltd
PY - 2010/2
Y1 - 2010/2
N2 - This study explored the association between vitamin D insufficiency and frailty syndrome defined by the Fried Frailty Index (FFI) and the Edmonton Frail Scale (EFS) in a northern Taiwan community. Data of 215 subjects participating in an integrated interventional trial involving community-dwelling older adults with a high frailty risk were analyzed. Subjects were first screened by telephone interview and then evaluated at a local hospital with questionnaires, physical performance tests, and serum 25(OH)D measurements. Of the 215 participants, 31% had 25(OH)D insufficiency (< 20 ng/ml). Frail subjects based on the FFI were older, had lower Mini-Mental Status Exam (MMSE) scores, Barthel Index (BI) scores, and 25(OH)D levels. Using the EFS, frailer cases were more likely to be female, have less education, higher comorbid conditions, lower MMSE scores, lower Barthel Index scores, and lower 25(OH)D levels. The associations between insufficient 25(OH)D status and both frailty scales were significant. After adjustment of variables, the odds ratio of 25(OH)D insufficiency was 10.74 (95% CI 2.60–44.31) for frail versus robust individuals. The prevalence of vitamin D insufficiency was high in this population. There was a strong association between vitamin D insufficiency and the FFI. Vitamin D measurements and supplements are suggested for high-risk older people.
AB - This study explored the association between vitamin D insufficiency and frailty syndrome defined by the Fried Frailty Index (FFI) and the Edmonton Frail Scale (EFS) in a northern Taiwan community. Data of 215 subjects participating in an integrated interventional trial involving community-dwelling older adults with a high frailty risk were analyzed. Subjects were first screened by telephone interview and then evaluated at a local hospital with questionnaires, physical performance tests, and serum 25(OH)D measurements. Of the 215 participants, 31% had 25(OH)D insufficiency (< 20 ng/ml). Frail subjects based on the FFI were older, had lower Mini-Mental Status Exam (MMSE) scores, Barthel Index (BI) scores, and 25(OH)D levels. Using the EFS, frailer cases were more likely to be female, have less education, higher comorbid conditions, lower MMSE scores, lower Barthel Index scores, and lower 25(OH)D levels. The associations between insufficient 25(OH)D status and both frailty scales were significant. After adjustment of variables, the odds ratio of 25(OH)D insufficiency was 10.74 (95% CI 2.60–44.31) for frail versus robust individuals. The prevalence of vitamin D insufficiency was high in this population. There was a strong association between vitamin D insufficiency and the FFI. Vitamin D measurements and supplements are suggested for high-risk older people.
KW - Edmonton Frail Scale
KW - Elderly in Taiwan
KW - Fried Frailty Index
KW - Vitamin D insufficiency
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U2 - 10.1016/S0167-4943(10)70006-6
DO - 10.1016/S0167-4943(10)70006-6
M3 - Article
C2 - 20171450
AN - SCOPUS:77952538830
SN - 0167-4943
VL - 50
SP - S17-S21
JO - Archives of Gerontology and Geriatrics
JF - Archives of Gerontology and Geriatrics
ER -