Viral infection, psychopathology, and autonomic modulation among methadone users in Taiwan

Wei Lieh Huang; Li Ren Chang; Terry B.J. Kuo; Yu Hsuan Lin; Jia Ling Yang; Ying Zai Chen; Cheryl C.H. Yang

Viral infection, psychopathology, and autonomic modulation among methadone users in Taiwan

Wei Lieh Huang, Li Ren Chang, Terry B.J. Kuo, Yu Hsuan Lin, Jia Ling Yang, Ying Zai Chen, Cheryl C.H. Yang

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: We aimed to explore the impact of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection on autonomic modulation in heroin users. Methods: Fifty-nine subjects were divided into three groups: no infection group, HCV infection group, and HIV infection group (IG). Heart rate variability of all participants was measured. Results: The high frequency power (a parasympathetic index) and the total power (a combined autonomic index) of the IG were significantly lower before and after taking methadone. Above finding could not be explained by psychopathology. Conclusions: The results indicated that early HIV infection may play a role in autonomic dysregulation in heroin users.

Original language	English
Pages (from-to)	31-38
Number of pages	8
Journal	Heroin Addiction and Related Clinical Problems
Volume	19
Issue number	6
Publication status	Published - Dec 1 2017
Externally published	Yes

Keywords

Heart rate variability
Hepatitis C virus
Human immunodeficiency virus
Methadone

ASJC Scopus subject areas

Medicine (miscellaneous)
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Viral infection, psychopathology, and autonomic modulation among methadone users in Taiwan",

abstract = "Aim: We aimed to explore the impact of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection on autonomic modulation in heroin users. Methods: Fifty-nine subjects were divided into three groups: no infection group, HCV infection group, and HIV infection group (IG). Heart rate variability of all participants was measured. Results: The high frequency power (a parasympathetic index) and the total power (a combined autonomic index) of the IG were significantly lower before and after taking methadone. Above finding could not be explained by psychopathology. Conclusions: The results indicated that early HIV infection may play a role in autonomic dysregulation in heroin users.",

keywords = "Heart rate variability, Hepatitis C virus, Human immunodeficiency virus, Methadone",

author = "Huang, {Wei Lieh} and Chang, {Li Ren} and Kuo, {Terry B.J.} and Lin, {Yu Hsuan} and Yang, {Jia Ling} and Chen, {Ying Zai} and Yang, {Cheryl C.H.}",

year = "2017",

month = dec,

day = "1",

language = "English",

volume = "19",

pages = "31--38",

journal = "Heroin Addiction and Related Clinical Problems",

issn = "1592-1638",

publisher = "Pacini Editore s.r.l.",

number = "6",

}

TY - JOUR

T1 - Viral infection, psychopathology, and autonomic modulation among methadone users in Taiwan

AU - Huang, Wei Lieh

AU - Chang, Li Ren

AU - Kuo, Terry B.J.

AU - Lin, Yu Hsuan

AU - Yang, Jia Ling

AU - Chen, Ying Zai

AU - Yang, Cheryl C.H.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Aim: We aimed to explore the impact of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection on autonomic modulation in heroin users. Methods: Fifty-nine subjects were divided into three groups: no infection group, HCV infection group, and HIV infection group (IG). Heart rate variability of all participants was measured. Results: The high frequency power (a parasympathetic index) and the total power (a combined autonomic index) of the IG were significantly lower before and after taking methadone. Above finding could not be explained by psychopathology. Conclusions: The results indicated that early HIV infection may play a role in autonomic dysregulation in heroin users.

AB - Aim: We aimed to explore the impact of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection on autonomic modulation in heroin users. Methods: Fifty-nine subjects were divided into three groups: no infection group, HCV infection group, and HIV infection group (IG). Heart rate variability of all participants was measured. Results: The high frequency power (a parasympathetic index) and the total power (a combined autonomic index) of the IG were significantly lower before and after taking methadone. Above finding could not be explained by psychopathology. Conclusions: The results indicated that early HIV infection may play a role in autonomic dysregulation in heroin users.

KW - Heart rate variability

KW - Hepatitis C virus

KW - Human immunodeficiency virus

KW - Methadone

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M3 - Article

AN - SCOPUS:85035199597

SN - 1592-1638

VL - 19

SP - 31

EP - 38

JO - Heroin Addiction and Related Clinical Problems

JF - Heroin Addiction and Related Clinical Problems

IS - 6

ER -

Viral infection, psychopathology, and autonomic modulation among methadone users in Taiwan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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