TY - JOUR
T1 - Using temperature-time integration as a critical parameter in using monopolar radiofrequency ablations
AU - Chang, Yen Liang
AU - Tseng, Te Ming
AU - Chen, Po Yueh
AU - Lin, Chun Ju
AU - Hung, Shih-Han
PY - 2014/7
Y1 - 2014/7
N2 - It is generally believed that radiofrequency energy delivered to the tissue determines the RFA lesion size. The purpose of this study was to re-evaluate this relationship and propose a potentially parameter of temperature-time integration as a better indicator of RFA lesion size. Using an Ex Vivo lesioning model, fixed 300 J RFA lesions were created under target temperature settings of 65, 75, and 85°C. The lesion sizes were recorded and compared. Under the target temperature of 65 and 75°C, the RFA procedures were sustained for a period of time after reaching the target temperature. The correlation between the lesion size and the sustained time (Ts) after reaching the target temperature was calculated. Under the same amount of energy output (300 J), the lesion size created under the three different target temperatures (65, 75, and 85°C) differs significantly. When the target temperature was set to 75°C, the correlation coefficient between the Ts and the lesion area and the maximal effective radius (Mer) were 0.913 and 0.971, respectively. When the target temperature was set to 65°C, the correlation coefficient between the Ts and the lesion area and the Mer were 0.962 and 0.923, respectively. The RFA lesion size is not proportional to the total delivered energy. The Temperature-time integration appears to be a much better indicator that critically influences the lesion size.
AB - It is generally believed that radiofrequency energy delivered to the tissue determines the RFA lesion size. The purpose of this study was to re-evaluate this relationship and propose a potentially parameter of temperature-time integration as a better indicator of RFA lesion size. Using an Ex Vivo lesioning model, fixed 300 J RFA lesions were created under target temperature settings of 65, 75, and 85°C. The lesion sizes were recorded and compared. Under the target temperature of 65 and 75°C, the RFA procedures were sustained for a period of time after reaching the target temperature. The correlation between the lesion size and the sustained time (Ts) after reaching the target temperature was calculated. Under the same amount of energy output (300 J), the lesion size created under the three different target temperatures (65, 75, and 85°C) differs significantly. When the target temperature was set to 75°C, the correlation coefficient between the Ts and the lesion area and the maximal effective radius (Mer) were 0.913 and 0.971, respectively. When the target temperature was set to 65°C, the correlation coefficient between the Ts and the lesion area and the Mer were 0.962 and 0.923, respectively. The RFA lesion size is not proportional to the total delivered energy. The Temperature-time integration appears to be a much better indicator that critically influences the lesion size.
KW - Energy
KW - Lesion size
KW - Radiofrequency ablation
KW - Temperature control
KW - Temperature time
UR - http://www.scopus.com/inward/record.url?scp=84902258446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902258446&partnerID=8YFLogxK
U2 - 10.1007/s00405-014-2917-6
DO - 10.1007/s00405-014-2917-6
M3 - Article
C2 - 24500416
AN - SCOPUS:84902258446
SN - 0937-4477
VL - 271
SP - 1973
EP - 1979
JO - European Archives of Oto-Rhino-Laryngology
JF - European Archives of Oto-Rhino-Laryngology
IS - 7
ER -