Using dynamic analysis of Laser-Doppler blood fowmetry to measure nasal mucosa bloody fow in postural changes

Background: The regulation of nasal mucosa blood fow (NMBF) is afected by multiple factors, such as the autonomic nervous system, medications, temperature, humidity, endocrine, even emotional stress and vision. The efects of postural changes on NMBF have been described in numerous studies. However, the results are far from consistent due to diferent experimental designs. Objective: Dynamic analysis of Laser-Doppler blood fowmetry (LDBF) is employed to recognize the efect of postural changes on NMBF. Methods: NMBF was continuously measured by LDBF in 14 participants with changing postures (sitting and supine). NMBF was measured in Blood Perfusion Unit (BPU), equivalent to the number of red blood cells multiplied by their mean velocity in a measured volume. Results: NMBF increases signifcantly in a supine posture compared with that in a sitting posture. Conclusion: Our study demonstrates that NMBF is signifcantly infuenced after initial postural change, suggesting that hanges in posture may be regarded as an important factor regulating NMBF.