TY - JOUR
T1 - Usefulness of Thallium-201 SPECT Scintimammography to Differentiate Benign from Malignant Breast Masses in Mammographically Dense Breasts
AU - Chiou, Jeng F.
AU - Lin, Ming C.
AU - Chen, Dar R.
AU - Jim, Yick F.
AU - Kao, Chia H.
PY - 2003
Y1 - 2003
N2 - The purpose of this study was to assess the usefulness of thallium-201 (Tl-201) single-photon emission-computed tomography (SPECT) scintimammography to differentiate benign from malignant breast masses in 32 female Taiwanese patients with indeterminate mammographic probability of malignancy because of mammographically dense breasts. All breast masses were removed, and final histopathological diagnoses were obtained in all cases. The results showed that thallium-201 SPECT scintimammography findings were true-positive in 22 cases, false-positive in 1 case, true-negative in 7 cases, and false-negative in 2 cases. The diagnostic sensitivity, specificity, and accuracy were 91.7%, 87.5%, and 90.6%, respectively, for detecting breast cancer in mammographically dense breasts. In conclusion, thallium-201 SPECT scintimammography is a useful tool for differentiating benign from malignant breast masses in patients with indeterminate mammograms because of mammographically dense breasts.
AB - The purpose of this study was to assess the usefulness of thallium-201 (Tl-201) single-photon emission-computed tomography (SPECT) scintimammography to differentiate benign from malignant breast masses in 32 female Taiwanese patients with indeterminate mammographic probability of malignancy because of mammographically dense breasts. All breast masses were removed, and final histopathological diagnoses were obtained in all cases. The results showed that thallium-201 SPECT scintimammography findings were true-positive in 22 cases, false-positive in 1 case, true-negative in 7 cases, and false-negative in 2 cases. The diagnostic sensitivity, specificity, and accuracy were 91.7%, 87.5%, and 90.6%, respectively, for detecting breast cancer in mammographically dense breasts. In conclusion, thallium-201 SPECT scintimammography is a useful tool for differentiating benign from malignant breast masses in patients with indeterminate mammograms because of mammographically dense breasts.
KW - Breast cancer
KW - Dense breast
KW - Single-photon emission-computed tomography (SPECT)
KW - Thallium-201 (Tl-201)
UR - http://www.scopus.com/inward/record.url?scp=0346727421&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0346727421&partnerID=8YFLogxK
U2 - 10.1081/CNV-120025089
DO - 10.1081/CNV-120025089
M3 - Article
C2 - 14735690
AN - SCOPUS:0346727421
SN - 0735-7907
VL - 21
SP - 863
EP - 868
JO - Cancer Investigation
JF - Cancer Investigation
IS - 6
ER -
