Uric acid stimulates endothelin-1 gene expression associated with NADPH oxidase in human aortic smooth muscle cells

Medicine & Life Sciences

• NADPH Oxidases 100%
• Endothelin-1 94%
• Uric Acid 88%
• Smooth Muscle Myocytes 76%
• Gene Expression 52%
• Cell Proliferation 17%
• Transcription Factor AP-1 14%
• Extracellular Signal-Regulated MAP Kinases 14%
• Vascular Diseases 13%
• Oxidation-Reduction 12%
• 1,3-butadiene 10%
• 4-ethoxymethylene-2-phenyl-2-oxazoline-5-one 9%
• Cardiovascular Diseases 9%
• acetovanillone 9%
• Phosphorylation 9%
• Hypertension 8%
• U 0126 8%
• Hyperuricemia 8%
• Mitogen-Activated Protein Kinase 3 7%
• Acetylcysteine 7%
• Protein Binding 6%
• Small Interfering RNA 5%
• Reactive Oxygen Species 5%
• Binding Sites 5%
• Transcription Factors 5%
• Antioxidants 4%
• Observation 4%
• Blood Vessels 3%
• Genes 2%