Abstract
BACKGROUND: The cardiovascular effects on fibrinolytic activity by urban air pollution are still unknown. METHODS: Paired fasting blood samples during high and low air pollution days in Taipei were taken from a panel of 49 patients with coronary heart disease or multiple risk factors to study their fibrinolytic and inflammatory response to urban air pollution. Paired t-tests and mixed-effects models were used to determine the air pollution effects. RESULTS: Patients' plasma plasminogen activator inhibitor-1 levels were significantly increased when hourly concentrations of particulate matter with diameters less than 10 μm (PM10) were greater than 100 μg/m during the period 0800 to 1800 h. CONCLUSION: Urban air pollution has an adverse effect on plasma fibrinolytic function in a susceptible population.
Original language | English |
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Pages (from-to) | 849-852 |
Number of pages | 4 |
Journal | European Journal of Cardiovascular Prevention and Rehabilitation |
Volume | 13 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 2006 |
Externally published | Yes |
Keywords
- Fibrinogen
- Inflammation marker
- Particulate matter
- Plasminogen activator inhibitor-1
- Urban air pollution
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Rehabilitation
- Public Health, Environmental and Occupational Health