Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

Chih Hsin Lee; Jann Yuan Wang; Kuo Liang Huang; Hung Wen Chiu; Tsung Ching Fei; Tsui Shia Chen; Hung Chang

doi:10.1097/TA.0b013e3181d7685a

Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

Chih Hsin Lee, Jann Yuan Wang, Kuo Liang Huang, Hung Wen Chiu, Tsung Ching Fei, Tsui Shia Chen, Hung Chang

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

Original language	English
Pages (from-to)	1357-1361
Number of pages	5
Journal	Journal of Trauma - Injury, Infection and Critical Care
Volume	68
Issue number	6
DOIs	https://doi.org/10.1097/TA.0b013e3181d7685a
Publication status	Published - Jun 2010

Keywords

Arterial pressure
Cardiac output
Hemodynamic monitoring
Model
Pig
Thermodilution

ASJC Scopus subject areas

Surgery
Critical Care and Intensive Care Medicine

Access to Document

10.1097/TA.0b013e3181d7685a

Cite this

@article{d18503ef47954545b0f3a407ac6f26da,

title = "Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion",

abstract = "Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value ",

keywords = "Arterial pressure, Cardiac output, Hemodynamic monitoring, Model, Pig, Thermodilution",

author = "Lee, {Chih Hsin} and Wang, {Jann Yuan} and Huang, {Kuo Liang} and Chiu, {Hung Wen} and Fei, {Tsung Ching} and Chen, {Tsui Shia} and Hung Chang",

year = "2010",

month = jun,

doi = "10.1097/TA.0b013e3181d7685a",

language = "English",

volume = "68",

pages = "1357--1361",

journal = "Journal of Trauma - Injury, Infection and Critical Care",

issn = "0022-5282",

publisher = "Lippincott Williams and Wilkins",

number = "6",

}

TY - JOUR

T1 - Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

AU - Lee, Chih Hsin

AU - Wang, Jann Yuan

AU - Huang, Kuo Liang

AU - Chiu, Hung Wen

AU - Fei, Tsung Ching

AU - Chen, Tsui Shia

AU - Chang, Hung

PY - 2010/6

Y1 - 2010/6

N2 - Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

AB - Background: Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent. This study was conducted to determine whether pulse contour-derived cardiac output truly reflects rapid hemodynamic changes. Methods: Hemorrhagic shock was created in seven anesthetized piglets by continuous blood withdrawal at a rate of 1 mL • kg • min for 20 minutes. Volume expansion with 10% hydroxyethyl starch 8 mL • kg was then administered for 5 minutes. Pulse contour-derived and thermodilution- derived hemodynamic parameters were compared. Results: Baseline thermodilution-derived cardiac index was 3.2 ± 0.4 L • min • M. After exsanguination, it decreased to 2.1 ± 0.3 L • min • M while pulse contour-derived cardiac index increased to 4.4 ± 0.4 L • min • M (p value

KW - Arterial pressure

KW - Cardiac output

KW - Hemodynamic monitoring

KW - Model

KW - Pig

KW - Thermodilution

UR - http://www.scopus.com/inward/record.url?scp=77953734974&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953734974&partnerID=8YFLogxK

U2 - 10.1097/TA.0b013e3181d7685a

DO - 10.1097/TA.0b013e3181d7685a

M3 - Article

C2 - 20539180

AN - SCOPUS:77953734974

SN - 0022-5282

VL - 68

SP - 1357

EP - 1361

JO - Journal of Trauma - Injury, Infection and Critical Care

JF - Journal of Trauma - Injury, Infection and Critical Care

IS - 6

ER -

Unreliability of pulse contour-derived cardiac output in piglets simulating acute hemorrhagic shock and rapid volume expansion

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this