Unilateral generalized morphea: First case report in Taiwan

Meng Che Lu, Shyh Dar Shyur, Lee Wen Lee, Timothy Hsu

Research output: Contribution to journalComment/debatepeer-review


Generalized morphea (GM) is a subtype of localized scleroderma that usually manifests with bilateral involvement. Unilateral generalized morphea (UGM) is a rare variant of GM. This is a case report of a Taiwanese girl with UGM over the left side of her body. She presented with hyperpigmentation, tightness, and skin atrophy over the left extremities and trunk. Mild range of motion (ROM) limitation over the left knee was also noted. At the clinic, the patient was given oral prednisolone, oral methotrexate (MTX), and oral D-penicillamine. topical emollient and topical glucocorticoids were also given. The dose of oral prednisolone was tapered gradually. All symptoms were improved under the treatment and regular rehabilitation program. To date, there is very little evidence to form the basis for treatment recommendations. This case report provides a treatment option for UGM in the paediatric group without the use of intravenous methylpred-nisolone pulse therapy.

Original languageEnglish
Pages (from-to)120-123
Number of pages4
JournalAsian Pacific Journal of Allergy and Immunology
Issue number2
Publication statusPublished - 2020


  • Child
  • Generalized morphea
  • Localized scleroderma
  • Morphea
  • Paediatrics
  • Scleroderma

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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