Ultrasound diagnosis of transverse sinus hypoplasia using flow profiles of the internal jugular vein

A. Ching Chao, Ke Han, Feng Chi Chang, Hung Yi Hsu, Chih Ping Chung, Wen Yung Sheng, Lung Chan, Jiang Wu, Han Hwa Hu

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Accurate diagnosis of subtypes of transverse sinus (TS) hypoplasia requires more expensive methods like magnetic resonance (MR) imaging. We hypothesized ultrasound findings of the internal jugular vein (IJV) can be surrogate indicators for diagnosis of TS hypoplasia. MR images were reviewed in 131 subjects to evaluate TS diameter and the location and degree of venous flow stenosis and obstruction. Ultrasound parameters including the crosssectional lumen area (CSA), time-average-mean velocity (TAMV), and flow volume (FV) at each IJV segment were also evaluated. Sixty-nine subjects had TS hypoplasia based on MRV criteria, of which 39 TS hypoplasia were considered a subtype of TS hypoplasia, which is secondary to the downstream venous compression/stenosis or left brachiocephalic vein. In the ultrasound study, the CSA of the IJV ipsilateral to TS hypoplasia was significantly smaller. Further, a contralateral/ipsilateral IJV CSA ratio >1.55 provided good sensitivity, specificity, and positive predictive value for discriminating TS hypoplasia.

Original languageEnglish
Article numbere0181119
JournalPLoS One
Issue number7
Publication statusPublished - Jul 1 2017

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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