TY - JOUR
T1 - Ultrasonographic alterations associated with the dilatation of mammary ducts
T2 - Feature analysis and BI-RADS assessment
AU - Hsu, Hsian He
AU - Yu, Jyh Cherng
AU - Hsu, Giu Cheng
AU - Chang, Wei Chou
AU - Yu, Cheng Ping
AU - Tung, Ho Jui
AU - Tzao, Ching
AU - Huang, Guo Shu
PY - 2010/2
Y1 - 2010/2
N2 - Objective: The purpose of this study was to analyse the lesion characteristics and the patterns of dilated ducts on ultrasonography (US) to determine the appropriateness of the Breast Imaging Reporting and Data System (BI-RADS) categories. Materials and methods: From July 2001 to June 2006, 172 consecutive pathologically proved lesions with dilated ducts on US were reviewed retrospectively. All the lesions were classified into four types according to their US features, and in combination with the size, location, margins and number of lesions, the corresponding positive predictive values (PPVs) were obtained. Results: Of the 172 lesions, 55 (32%) were classified as type I, 68 (40%) as type II, 14 (8%) as type III and 35 (20%) as type IV. The PPVs for malignancy were 9% for type I, 13% for type II, 43% for type III and 17% for type IV. There was a significantly higher frequency of malignancy among type III lesions than among type I (43% vs 9%, respectively, P=0.002; Χ2 test) or type II lesions (43% vs 13%, respectively, P=0.009; Χ2 test). Lesions with a nonsubareolar location and noncircumscribed margins had a high probability of malignancy (P<0.001 and P=0.03, respectively). Conclusion: The four types of US classifications used in our study establish reliable references for the dilated duct patterns when stratified according to BI-RADS categories, and they clarify the indications for biopsy of these lesions.
AB - Objective: The purpose of this study was to analyse the lesion characteristics and the patterns of dilated ducts on ultrasonography (US) to determine the appropriateness of the Breast Imaging Reporting and Data System (BI-RADS) categories. Materials and methods: From July 2001 to June 2006, 172 consecutive pathologically proved lesions with dilated ducts on US were reviewed retrospectively. All the lesions were classified into four types according to their US features, and in combination with the size, location, margins and number of lesions, the corresponding positive predictive values (PPVs) were obtained. Results: Of the 172 lesions, 55 (32%) were classified as type I, 68 (40%) as type II, 14 (8%) as type III and 35 (20%) as type IV. The PPVs for malignancy were 9% for type I, 13% for type II, 43% for type III and 17% for type IV. There was a significantly higher frequency of malignancy among type III lesions than among type I (43% vs 9%, respectively, P=0.002; Χ2 test) or type II lesions (43% vs 13%, respectively, P=0.009; Χ2 test). Lesions with a nonsubareolar location and noncircumscribed margins had a high probability of malignancy (P<0.001 and P=0.03, respectively). Conclusion: The four types of US classifications used in our study establish reliable references for the dilated duct patterns when stratified according to BI-RADS categories, and they clarify the indications for biopsy of these lesions.
KW - BI-RADS
KW - Breast carcinoma
KW - Breast sonography
KW - Breast ultrasound
KW - Dilated mammary duct
KW - Intraductal papillary lesion
UR - https://www.scopus.com/pages/publications/77951243220
UR - https://www.scopus.com/inward/citedby.url?scp=77951243220&partnerID=8YFLogxK
U2 - 10.1007/s00330-009-1546-8
DO - 10.1007/s00330-009-1546-8
M3 - Article
C2 - 19707771
AN - SCOPUS:77951243220
SN - 0938-7994
VL - 20
SP - 293
EP - 302
JO - European Radiology
JF - European Radiology
IS - 2
ER -