Abstract
This paper describes the progress in our efforts at producing ultra-high resolution (< 0.8 A) DNA structures using advanced cryo-crystallography and synchrotron. Our work is aimed at providing reliable geometric (bond length and bond angle), electronic and motional information of DNA molecules in different conformational contexts. These highly-reliable, new structures will be the basis for constructing better DNA force-field parameters, which will benefit the structural refinement of DNA, protein-DNA complexes, and ligand-DNA complexes.
| Original language | English |
|---|---|
| Pages (from-to) | 151-152 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series |
| Issue number | 42 |
| DOIs | |
| Publication status | Published - 1999 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Medicine