Ultra-high resolution DNA structures.

A. H. Wang, H. Robinson, Y. G. Gao

Research output: Contribution to journalArticlepeer-review

Abstract

This paper describes the progress in our efforts at producing ultra-high resolution (< 0.8 A) DNA structures using advanced cryo-crystallography and synchrotron. Our work is aimed at providing reliable geometric (bond length and bond angle), electronic and motional information of DNA molecules in different conformational contexts. These highly-reliable, new structures will be the basis for constructing better DNA force-field parameters, which will benefit the structural refinement of DNA, protein-DNA complexes, and ligand-DNA complexes.

Original languageEnglish
Pages (from-to)151-152
Number of pages2
JournalNucleic acids symposium series
Issue number42
DOIs
Publication statusPublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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