Abstract
From the methanolic extract of the leaves of Planchonella duclitan, 2α,3α,19α,23-tetrahydroxy-13,27-cyclours-11-en-28-oic acid(1), myrianthic acid (2), 2-hydroxyursolic acid (3), ursolic acid (4), pomolic acid (5), rotundic acid (6), and jacoumaric acid (7) were isolated, and their structures were elucidated on the basis of their spectroscopic analysis. Among them, compound 1 was a new cyclopropyl ursane-type triterpene acid. Additionally, compounds 4 and 7 showed significant cytotoxicity toward human colorectal carcinoma cell line HT29 and human breast carcinoma cell line MCF-7 with IC50 values ranging from 5.8 ± 1.4 to 6.5 ± 1.9 μM.
| Original language | English |
|---|---|
| Pages (from-to) | 1275-1280 |
| Number of pages | 6 |
| Journal | Journal of the Chinese Chemical Society |
| Volume | 52 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2005 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- 2α,3α,19α,23-tetrahydroxy-13,27-cyclours-11-en-28-oic acid
- HT29
- Leaves
- MCF-7
- Planchonella duclitan
- Sapotaceae
- Triterpene acids
ASJC Scopus subject areas
- General Chemistry
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