TY - JOUR
T1 - Treatment profile and complications associated with cryotherapy for localized prostate cancer
T2 - A population-based study
AU - Roberts, C. B.
AU - Jang, T. L.
AU - Shao, Yu Hsuan
AU - Kabadi, S.
AU - Moore, D. F.
AU - Lu-Yao, G. L.
N1 - Funding Information:
We acknowledge the efforts of the Applied Research Branch, Division of Cancer Prevention and Population Science, NCI; the Office of Information Services and the Office of Strategic Planning, CMS; Information Management Services (IMS), Inc.; and the Surveillance, Epidemiology and End Results (SEER) Program tumor registries in the creation of the SEER-Medicare database. The performance and design of this study was reviewed and approved by both the National Cancer Institute (NCI) and Center for Medicare and Medicaid Services (CMS). This study was supported by an award from the Robert Wood Johnson Foundation grant #60624 and by the biometric Shared Resource(s) of The Cancer Institute of New Jersey (P30CA072720).
PY - 2011/12
Y1 - 2011/12
N2 - The aim of this study was to assess the treatment patterns and 3-12-month complication rates associated with receiving prostate cryotherapy in a population-based study. Men 65 years diagnosed with incident localized prostate cancer in Surveillance Epidemiology End Results (SEER)-Medicare-linked database from 2004 to 2005 were identified. A total of 21 344 men were included in the study, of which 380 were treated initially with cryotherapy. Recipients of cryotherapy versus aggressive forms of prostate therapy (ie, radical prostatectomy or radiation therapy) were more likely to be older, have one co-morbidity, low income, live in the South and be diagnosed with indolent cancer. Complication rates increased from 3 to 12 months following cryotherapy. By the twelth month, the rates for urinary incontinence, lower urinary tract obstruction, erectile dysfunction and bowel bleeding reached 9.8, 28.7, 20.1 and 3.3%, respectively. Diagnoses of hydronephrosis, urinary fistula or bowel fistula were not evident. The rates of corrective invasive procedures for lower urinary tract obstruction and erectile dysfunction were both
AB - The aim of this study was to assess the treatment patterns and 3-12-month complication rates associated with receiving prostate cryotherapy in a population-based study. Men 65 years diagnosed with incident localized prostate cancer in Surveillance Epidemiology End Results (SEER)-Medicare-linked database from 2004 to 2005 were identified. A total of 21 344 men were included in the study, of which 380 were treated initially with cryotherapy. Recipients of cryotherapy versus aggressive forms of prostate therapy (ie, radical prostatectomy or radiation therapy) were more likely to be older, have one co-morbidity, low income, live in the South and be diagnosed with indolent cancer. Complication rates increased from 3 to 12 months following cryotherapy. By the twelth month, the rates for urinary incontinence, lower urinary tract obstruction, erectile dysfunction and bowel bleeding reached 9.8, 28.7, 20.1 and 3.3%, respectively. Diagnoses of hydronephrosis, urinary fistula or bowel fistula were not evident. The rates of corrective invasive procedures for lower urinary tract obstruction and erectile dysfunction were both
KW - Medicare
KW - Surveillance Epidemiology and End Results Program
KW - cryotherapy
KW - prostatic neoplasms
UR - http://www.scopus.com/inward/record.url?scp=80955134037&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80955134037&partnerID=8YFLogxK
U2 - 10.1038/pcan.2011.17
DO - 10.1038/pcan.2011.17
M3 - Article
C2 - 21519347
AN - SCOPUS:80955134037
SN - 1365-7852
VL - 14
SP - 313
EP - 319
JO - Prostate Cancer and Prostatic Diseases
JF - Prostate Cancer and Prostatic Diseases
IS - 4
ER -
