Objective: Both nucleoplasty and epidural neuroplasty have emerged as minimally invasive techniques for treatment of low back pain and sciatica due to contained herniated discs. Although there were some studies examining their effects on functional activity and pain medications, the results of a combination of the two procedures have not been analyzed as yet. The aim of our study was to evaluate the outcome of a combination therapy in patients with chronic discogenic pain or sciatica due to nerve root compression by a single-level, contained herniated disc. Methods: Twenty-nine patients who had undergone the combination therapy of both nucleoplasty and epidural neuroplasty were included in the analysis and were evaluated at 3, 6, and 12 months postoperatively. They were asked to quantify their pain using a visual analog scale ranging from 0 to 10. The Oswestry Disability Index (ODI) was used to quantify disability by third-party observers. Patients were also surveyed with regard to their use of pain medications. We compared the data at 3, 6, and 12 months posttreatment to the baseline.
Results: There was a significant decrease in pain and use of medications in our study group. The functional status was improved at 3, 6, and 12 months. There were no complications associated with the procedure and we found continued improvements over time in the study group.
Conclusion: Nucleoplasty and epidurolysis in combination appear to be safe and effective in both early and later post-treatment periods. Further randomized, controlled studies are required to evaluate the long-term efficacy of the combination therapy.
Translated title of the contribution針對慢性椎間盤疼痛的病患以椎間盤整形術合併硬膜上沾粘清除術治療之一年期預後
Original languageEnglish
Pages (from-to)120-128
Number of pages9
JournalFormosan Journal of Surgery
Issue number3
Publication statusPublished - 2010


  • discectomy
  • disc herniation
  • low back pain
  • minimally invasive
  • nucleoplasty
  • percutaneous disc decompression
  • caudal neuroplasty and epidurolysis


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