Transcatheter closure of moderate-to-large patent ductus arteriosus in infants using amplatzer duct occluder

Jou Kou Wang, Mei Hwan Wu, Ming Tai Lin, Shuenn Nan Chiu, Chun An Chen, Hsin Hui Chiu

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)


Background: There are difficulties in transcatheter closure of patent ductus arteriosus (PDA) in infants. Methods and Results: The 46 infants (mean age 6.2±2.7 months; mean body weight 6.3±1.6 kg) who underwent PDA closure using the Amplatzer duct occluder (ADO). The indication for using an ADO was a ductus diameter ≥2.5 or 3 mm. Device diameter selected was 1-3 mm larger than ductal diameter. The mean systolic pulmonary artery pressure was 40.9±18.2 mmHg. The mean Qp/Qs ratio was 3.1±1.2. The mean ductus diameter was 3.3±0.8 mm. ADO was successfully deployed in 45 patients. Failure occurred in 1 case. The mean diameter of device used was 5.4±1.1 mm. No severe complications occurred. At the 1-month echocardiographic follow-up, a small residual shunt was present in 4 of 45 patients and had disappeared in all 4 patients at the 3-month followup. One patient developed a moderate degree of left ventricular outflow tract obstruction 2.3 years after the procedure. Conclusions: Transcatheter closure of PDA in infants using the ADO is a safe and effective method.

Original languageEnglish
Pages (from-to)361-364
Number of pages4
JournalCirculation Journal
Issue number2
Publication statusPublished - Feb 2010
Externally publishedYes


  • Amplatzer duct occluder
  • Infants
  • Patent ductus arteriosus
  • Transcatheter closure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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