Toe-lift test: a novel, simple and noninvasive in vivo method for contractile evaluation of tibialis anterior muscle

Chung Min Tsai, Yu Chun Lo, Chuang Yu Lin, Chun Yin Hou, Ya Li Huang, His Chang

Research output: Contribution to journalArticlepeer-review

Abstract

Tibialis anterior (TA) muscle has frequently been used for scientific experiments, particu-larly for muscle contractile assays, because of its anatomical advantages. However, classical evaluation methods for the TA muscle, such as EMG and force transducer, require experimental skills to acquire reliable results. Furthermore, because sacrificing experimental animals is usually indispensable for both methods, sequential observations cannot be performed. Therefore, developing a simple, objective, and animal friendly evaluation system was warranted. In this article, we introduce a novel, simple, and noninvasive in vivo evaluation method for the TA muscle called the toe-lift test (TLT), which is not only easy to perform but also capable of detecting contractile strength precisely. Because the TLT does not require experimental animal sacrifice, performing assessments over time, such as in sequential observation, is possible. This novel method represents a solution to the need for a simple, noninvasive, and effective method for TA muscle contractile evaluation.

Original languageEnglish
Pages (from-to)339-347
Number of pages9
JournalGeneral Physiology and Biophysics
Volume41
Issue number4
DOIs
Publication statusPublished - 2022

Keywords

  • Contractile evaluation
  • Electromyography
  • Force transducer
  • Nociceptive withdrawal reflex
  • Tibialis anterior muscle

ASJC Scopus subject areas

  • Biophysics
  • Physiology

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