TY - JOUR
T1 - Tinnitus and risk of attempted suicide
T2 - A one year follow-up study
AU - Cheng, Yen Fu
AU - Xirasagar, Sudha
AU - Kuo, Nai Wen
AU - Lin, Herng Ching
N1 - Funding Information:
None. None.
Publisher Copyright:
© 2022 Elsevier B.V.
PY - 2023/2
Y1 - 2023/2
N2 - Background: Tinnitus causes emotional stress that can be extreme, bringing on anxiety, depression, or sleep disorders. We used a nationwide, population-based database to study the risk of attempted suicide among adults with tinnitus. Methods: Data for this retrospective cohort study were extracted from the Taiwan National Health Insurance Research Database, on 386,055 patients with tinnitus and propensity score-matched controls. We performed Cox proportional hazards regression analysis to calculate the one-year hazard of a suicide attempt and 95 % confidence intervals (CI) following a first-time diagnosis of tinnitus. Results: The results shows that the incidence of attempted suicide was 0.253 (95 % CI = 0.237–0.269) and 0.123 (95 % CI = 0.113–0.135) for the study cohort and comparison cohort, respectively. The log-rank test suggested that the study cohort had significantly lower suicide attempt-free survival at one year than the comparison cohort (p < 0.001). Cox proportional analysis shows that the hazard ratio of attempted suicide within the one-year follow-up period was 2.04 (95 % CI = 1.83–2.28) for patients with tinnitus than those in the comparison cohort after adjusting for the patients' age, sex, monthly income, geographic region, urbanization level of the patient's residence, hyperlipidemia, diabetes, coronary heart disease, and hypertension. Limitations: The database lacks information on socioeconomic problems, specific personal characteristics or traits, marital status, or other factors associated with attempts to commit suicide. Notably, our study addressed suicide attempts as detected from claims-based ICD codes which do not cover suicidal ideation or suicidal death. Conclusions: We found increased likelihood of attempted suicide among patients with tinnitus.
AB - Background: Tinnitus causes emotional stress that can be extreme, bringing on anxiety, depression, or sleep disorders. We used a nationwide, population-based database to study the risk of attempted suicide among adults with tinnitus. Methods: Data for this retrospective cohort study were extracted from the Taiwan National Health Insurance Research Database, on 386,055 patients with tinnitus and propensity score-matched controls. We performed Cox proportional hazards regression analysis to calculate the one-year hazard of a suicide attempt and 95 % confidence intervals (CI) following a first-time diagnosis of tinnitus. Results: The results shows that the incidence of attempted suicide was 0.253 (95 % CI = 0.237–0.269) and 0.123 (95 % CI = 0.113–0.135) for the study cohort and comparison cohort, respectively. The log-rank test suggested that the study cohort had significantly lower suicide attempt-free survival at one year than the comparison cohort (p < 0.001). Cox proportional analysis shows that the hazard ratio of attempted suicide within the one-year follow-up period was 2.04 (95 % CI = 1.83–2.28) for patients with tinnitus than those in the comparison cohort after adjusting for the patients' age, sex, monthly income, geographic region, urbanization level of the patient's residence, hyperlipidemia, diabetes, coronary heart disease, and hypertension. Limitations: The database lacks information on socioeconomic problems, specific personal characteristics or traits, marital status, or other factors associated with attempts to commit suicide. Notably, our study addressed suicide attempts as detected from claims-based ICD codes which do not cover suicidal ideation or suicidal death. Conclusions: We found increased likelihood of attempted suicide among patients with tinnitus.
KW - Attempted suicide
KW - Epidemiology
KW - Suicide
KW - Tinnitus
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U2 - 10.1016/j.jad.2022.11.009
DO - 10.1016/j.jad.2022.11.009
M3 - Article
C2 - 36372122
AN - SCOPUS:85142151465
SN - 0165-0327
VL - 322
SP - 141
EP - 145
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -