Thromboxane B2 transformed from arachidonic acid in carrageenin-induced granuloma

Wen Chang Chang; Sei itsu Murota; Susumu Tsurufuji

doi:10.1016/0090-6980(77)90038-7

Thromboxane B₂ transformed from arachidonic acid in carrageenin-induced granuloma

Wen Chang Chang, Sei itsu Murota, Susumu Tsurufuji

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).

Original language	English
Pages (from-to)	17-24
Number of pages	8
Journal	Prostaglandins
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/0090-6980(77)90038-7
Publication status	Published - Jan 1977
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Endocrinology

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abstract = "A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).",

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year = "1977",

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AU - Tsurufuji, Susumu

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AB - A main product (PI) transformed from arachidonic acid in carrageenin-induced granuloma in rats was structurally analysed. PI was converted to a more polar substance by the reduction with sodium borohydride. On the basis of the data on gas chromatography-mass spectrometry, its structure was identified with the hemiacetal derivative of 8-(1-hydroxy-3-oxopropyl)-9,12-heptadecadienoic acid (Thromboxane B2).

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Thromboxane B₂ transformed from arachidonic acid in carrageenin-induced granuloma

Abstract

ASJC Scopus subject areas

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