Three-dimensional brain images in preterm children with periventricular leukomalacia

Hsiao Feng Chou, Ming Fan Lin, Chia Yuan Chen, Ein Yiao Shen

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Background: To investigate the use of three-dimensional (3D) brain magnetic resonance imaging (MRI) to evaluate in preterm children with periventricular leukomalacia. Materials and Methods: Semiautomated 3D classification of the gray and white tissues was used to reconstruct brain images of patients with confirmed periventricular leukomalacia from 2D MRI. Results: We studied 14 preterm patients. The gestational age ranged from 25-37 weeks. The corrected age ranged from 5-49 months. We reconstructed the gray matter, white matter, and ventricles in order to analyze the brain volume. Conclusion: Three-dimensional MRI is a good tool that can be used to demonstrate brain lesions in stereo and differentiate the gray matter, white matter, and ventricles. Brain volume can also be accurately evaluated.

Original languageEnglish
Pages (from-to)45-48
Number of pages4
JournalPediatrics and Neonatology
Issue number1
Publication statusPublished - Feb 2012


  • 3D MRI
  • periventricular leukomalacia
  • preterm infant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Three-dimensional brain images in preterm children with periventricular leukomalacia'. Together they form a unique fingerprint.

Cite this