The use of transdermal fentanyl in cancer pain-A compliance study of outpatients in Taiwan

Tzeon Jye Chiou; Chun Yu Liu; Woan Fang Tzeng; Yu Chieh Su; Yih Chyang Weng; Chih Jen Hung; Yeh Tang; Yu Jen Chen

doi:10.1177/1049909109346427

The use of transdermal fentanyl in cancer pain-A compliance study of outpatients in Taiwan

Tzeon Jye Chiou, Chun Yu Liu, Woan Fang Tzeng, Yu Chieh Su, Yih Chyang Weng, Chih Jen Hung, Yeh Tang, Yu Jen Chen

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan. From 2005 to 2006, 822 outpatients received TTS-F to collect pain assessment forms and diaries for 4 weeks. Most (78.7%) patients were initially prescribed 25 μg/h TTS-F. Doses were adjusted weekly at clinicians' discretion, according to pain assessment and side effects. Patients receiving 50 μg/h, 75 μg/h, and > 75 μg/h TTS-F had increased from 17.5% to 32.1%, 1.8% to 3.4%, and 1.9% to 2.2%, respectively, by week 2; further small increases were found in weeks 3 and 4. Pain palliation improved from 60.6% during week 1 to 78.6% at week 4. The common adverse effects were nausea/vomiting. Patient's compliance was >90%. This study found that the TTS-F is effective and well tolerated.

Original language	English
Pages (from-to)	31-37
Number of pages	7
Journal	American Journal of Hospice and Palliative Medicine
Volume	27
Issue number	1
DOIs	https://doi.org/10.1177/1049909109346427
Publication status	Published - Feb 2010
Externally published	Yes

Keywords

Cancer patients
Cohort study
Compliance
Opioids analgesics
Side effects
Transdermal fentanyl

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1177/1049909109346427

Cite this

@article{4e58ea7f7fc442d2adaf146de0ad48e6,

title = "The use of transdermal fentanyl in cancer pain-A compliance study of outpatients in Taiwan",

abstract = "The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan. From 2005 to 2006, 822 outpatients received TTS-F to collect pain assessment forms and diaries for 4 weeks. Most (78.7%) patients were initially prescribed 25 μg/h TTS-F. Doses were adjusted weekly at clinicians' discretion, according to pain assessment and side effects. Patients receiving 50 μg/h, 75 μg/h, and > 75 μg/h TTS-F had increased from 17.5% to 32.1%, 1.8% to 3.4%, and 1.9% to 2.2%, respectively, by week 2; further small increases were found in weeks 3 and 4. Pain palliation improved from 60.6% during week 1 to 78.6% at week 4. The common adverse effects were nausea/vomiting. Patient's compliance was >90%. This study found that the TTS-F is effective and well tolerated.",

keywords = "Cancer patients, Cohort study, Compliance, Opioids analgesics, Side effects, Transdermal fentanyl",

author = "Chiou, {Tzeon Jye} and Liu, {Chun Yu} and Tzeng, {Woan Fang} and Su, {Yu Chieh} and Weng, {Yih Chyang} and Hung, {Chih Jen} and Yeh Tang and Chen, {Yu Jen}",

year = "2010",

month = feb,

doi = "10.1177/1049909109346427",

language = "English",

volume = "27",

pages = "31--37",

journal = "American Journal of Hospice and Palliative Medicine",

issn = "1049-9091",

publisher = "SAGE Publications Inc.",

number = "1",

}

TY - JOUR

T1 - The use of transdermal fentanyl in cancer pain-A compliance study of outpatients in Taiwan

AU - Chiou, Tzeon Jye

AU - Liu, Chun Yu

AU - Tzeng, Woan Fang

AU - Su, Yu Chieh

AU - Weng, Yih Chyang

AU - Hung, Chih Jen

AU - Tang, Yeh

AU - Chen, Yu Jen

PY - 2010/2

Y1 - 2010/2

N2 - The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan. From 2005 to 2006, 822 outpatients received TTS-F to collect pain assessment forms and diaries for 4 weeks. Most (78.7%) patients were initially prescribed 25 μg/h TTS-F. Doses were adjusted weekly at clinicians' discretion, according to pain assessment and side effects. Patients receiving 50 μg/h, 75 μg/h, and > 75 μg/h TTS-F had increased from 17.5% to 32.1%, 1.8% to 3.4%, and 1.9% to 2.2%, respectively, by week 2; further small increases were found in weeks 3 and 4. Pain palliation improved from 60.6% during week 1 to 78.6% at week 4. The common adverse effects were nausea/vomiting. Patient's compliance was >90%. This study found that the TTS-F is effective and well tolerated.

AB - The aim of this study is to investigate cancer patients' response and side effects associated with transdermal therapeutic fentanyl (TTS-F), whose pain was hardly controlled by nonweak/weak opioids in Taiwan. From 2005 to 2006, 822 outpatients received TTS-F to collect pain assessment forms and diaries for 4 weeks. Most (78.7%) patients were initially prescribed 25 μg/h TTS-F. Doses were adjusted weekly at clinicians' discretion, according to pain assessment and side effects. Patients receiving 50 μg/h, 75 μg/h, and > 75 μg/h TTS-F had increased from 17.5% to 32.1%, 1.8% to 3.4%, and 1.9% to 2.2%, respectively, by week 2; further small increases were found in weeks 3 and 4. Pain palliation improved from 60.6% during week 1 to 78.6% at week 4. The common adverse effects were nausea/vomiting. Patient's compliance was >90%. This study found that the TTS-F is effective and well tolerated.

KW - Cancer patients

KW - Cohort study

KW - Compliance

KW - Opioids analgesics

KW - Side effects

KW - Transdermal fentanyl

UR - http://www.scopus.com/inward/record.url?scp=75949112007&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=75949112007&partnerID=8YFLogxK

U2 - 10.1177/1049909109346427

DO - 10.1177/1049909109346427

M3 - Article

C2 - 19801533

AN - SCOPUS:75949112007

SN - 1049-9091

VL - 27

SP - 31

EP - 37

JO - American Journal of Hospice and Palliative Medicine

JF - American Journal of Hospice and Palliative Medicine

IS - 1

ER -

The use of transdermal fentanyl in cancer pain-A compliance study of outpatients in Taiwan

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this