The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Yu Ting Lin; Chia Hung Yen; Heng Li Chen; Yi Jen Liao; I. Feng Lin; Marcelo Chen; Yu Ching Lan; Shao Yuan Chuang; Shie Liang Hsieh; Yi Ming Arthur Chen

doi:10.1016/j.jfma.2013.01.007

The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Yu Ting Lin, Chia Hung Yen, Heng Li Chen, Yi Jen Liao, I. Feng Lin, Marcelo Chen, Yu Ching Lan, Shao Yuan Chuang, Shie Liang Hsieh, Yi Ming Arthur Chen

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p

Original language	English
Pages (from-to)	498-503
Number of pages	6
Journal	Journal of the Formosan Medical Association
Volume	114
Issue number	6
DOIs	https://doi.org/10.1016/j.jfma.2013.01.007
Publication status	Published - Jun 1 2015

Keywords

Decoy receptor 3 (DcR3)
Disease progression
HIV/AIDS
Subtype

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jfma.2013.01.007

Cite this

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title = "The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients",

abstract = "Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p",

keywords = "Decoy receptor 3 (DcR3), Disease progression, HIV/AIDS, Subtype",

author = "Lin, {Yu Ting} and Yen, {Chia Hung} and Chen, {Heng Li} and Liao, {Yi Jen} and Lin, {I. Feng} and Marcelo Chen and Lan, {Yu Ching} and Chuang, {Shao Yuan} and Hsieh, {Shie Liang} and Chen, {Yi Ming Arthur}",

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year = "2015",

month = jun,

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doi = "10.1016/j.jfma.2013.01.007",

language = "English",

volume = "114",

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T1 - The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

AU - Lin, Yu Ting

AU - Yen, Chia Hung

AU - Chen, Heng Li

AU - Liao, Yi Jen

AU - Lin, I. Feng

AU - Chen, Marcelo

AU - Lan, Yu Ching

AU - Chuang, Shao Yuan

AU - Hsieh, Shie Liang

AU - Chen, Yi Ming Arthur

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p

AB - Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p

KW - Decoy receptor 3 (DcR3)

KW - Disease progression

KW - HIV/AIDS

KW - Subtype

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The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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