Abstract
Background/Purpose: The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis. The goals of this study were to understand the associations between serologic DcR3 (sDcR3) levels and different human immunodeficiency virus type 1 (HIV-1) subtypes, as well as the AIDS disease progression. Methods: Serum samples from 61 HIV/AIDS patients, who had been followed up every 6 months for 3 years, were collected. sDcR3 levels were quantified using an enzyme immunoassay (EIA). Results: The sDcR3 levels in patients with HIV-1 subtype B were significantly higher than those in patients infected with subtype CRF01_AE (. p
Original language | English |
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Pages (from-to) | 498-503 |
Number of pages | 6 |
Journal | Journal of the Formosan Medical Association |
Volume | 114 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 1 2015 |
Keywords
- Decoy receptor 3 (DcR3)
- Disease progression
- HIV/AIDS
- Subtype
ASJC Scopus subject areas
- Medicine(all)