The review of bioeffects of static magnetic fields on the oral tissue-derived cells and its application in regenerative medicine

Wei Zhen Lew; Sheng Wei Feng; Sheng Yang Lee; Haw Ming Huang

doi:10.3390/cells10102662

The review of bioeffects of static magnetic fields on the oral tissue-derived cells and its application in regenerative medicine

Wei Zhen Lew, Sheng Wei Feng, Sheng Yang Lee, Haw Ming Huang

Research output: Contribution to journal › Review article › peer-review

23 Citations (Scopus)

Abstract

Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues. Various controversial pieces of evidence have been discussed regarding SMFs on cellular biophysics, but little consensus has been reached, especially in the field of dentistry. Thus, the present paper will first review the safe use of SMFs in the oral cavity and as an additive therapy to orthodontic tooth movement and periodontium regeneration. Then, studies regarding SMF-incorporated implants are reviewed to investigate the advantageous effects of SMFs on osseointegration and the underlying mechanisms. Finally, a review of current developments in dentistry surrounding the combination of magnetic nanoparticles (MNPs) and SMFs is made to clarify potential future clinical applications.

Original language	English
Article number	2662
Journal	Cells
Volume	10
Issue number	10
DOIs	https://doi.org/10.3390/cells10102662
Publication status	Published - Oct 2021

Keywords

Cytotoxicity
Differentiation
Magnetic nanoparticles
Magneto-mechanotrasduction
Oral tissue
Proliferation
Static magnetic fields

ASJC Scopus subject areas

General Medicine

Access to Document

10.3390/cells10102662

Cite this

@article{aa057dc36c2845ebae28c70f9847c26b,

title = "The review of bioeffects of static magnetic fields on the oral tissue-derived cells and its application in regenerative medicine",

abstract = "Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues. Various controversial pieces of evidence have been discussed regarding SMFs on cellular biophysics, but little consensus has been reached, especially in the field of dentistry. Thus, the present paper will first review the safe use of SMFs in the oral cavity and as an additive therapy to orthodontic tooth movement and periodontium regeneration. Then, studies regarding SMF-incorporated implants are reviewed to investigate the advantageous effects of SMFs on osseointegration and the underlying mechanisms. Finally, a review of current developments in dentistry surrounding the combination of magnetic nanoparticles (MNPs) and SMFs is made to clarify potential future clinical applications.",

keywords = "Cytotoxicity, Differentiation, Magnetic nanoparticles, Magneto-mechanotrasduction, Oral tissue, Proliferation, Static magnetic fields",

author = "Lew, {Wei Zhen} and Feng, {Sheng Wei} and Lee, {Sheng Yang} and Huang, {Haw Ming}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).",

year = "2021",

month = oct,

doi = "10.3390/cells10102662",

language = "English",

volume = "10",

journal = "Cells",

number = "10",

}

TY - JOUR

T1 - The review of bioeffects of static magnetic fields on the oral tissue-derived cells and its application in regenerative medicine

AU - Lew, Wei Zhen

AU - Feng, Sheng Wei

AU - Lee, Sheng Yang

AU - Huang, Haw Ming

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PY - 2021/10

Y1 - 2021/10

N2 - Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues. Various controversial pieces of evidence have been discussed regarding SMFs on cellular biophysics, but little consensus has been reached, especially in the field of dentistry. Thus, the present paper will first review the safe use of SMFs in the oral cavity and as an additive therapy to orthodontic tooth movement and periodontium regeneration. Then, studies regarding SMF-incorporated implants are reviewed to investigate the advantageous effects of SMFs on osseointegration and the underlying mechanisms. Finally, a review of current developments in dentistry surrounding the combination of magnetic nanoparticles (MNPs) and SMFs is made to clarify potential future clinical applications.

AB - Magnets have been widely used in dentistry for orthodontic tooth movement and denture retention. Nevertheless, criticisms have arisen regarding the biosafety of static magnetic field (SMF) effects on surrounding tissues. Various controversial pieces of evidence have been discussed regarding SMFs on cellular biophysics, but little consensus has been reached, especially in the field of dentistry. Thus, the present paper will first review the safe use of SMFs in the oral cavity and as an additive therapy to orthodontic tooth movement and periodontium regeneration. Then, studies regarding SMF-incorporated implants are reviewed to investigate the advantageous effects of SMFs on osseointegration and the underlying mechanisms. Finally, a review of current developments in dentistry surrounding the combination of magnetic nanoparticles (MNPs) and SMFs is made to clarify potential future clinical applications.

KW - Cytotoxicity

KW - Differentiation

KW - Magnetic nanoparticles

KW - Magneto-mechanotrasduction

KW - Oral tissue

KW - Proliferation

KW - Static magnetic fields

UR - http://www.scopus.com/inward/record.url?scp=85116325225&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85116325225&partnerID=8YFLogxK

U2 - 10.3390/cells10102662

DO - 10.3390/cells10102662

M3 - Review article

AN - SCOPUS:85116325225

VL - 10

JO - Cells

JF - Cells

IS - 10

M1 - 2662

ER -

The review of bioeffects of static magnetic fields on the oral tissue-derived cells and its application in regenerative medicine

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this