The randomized trials of breast cancer screening: What have we learned?

Robert A. Smith, Stephen W. Duffy, Rhian Gabe, Laszlo Tabar, Amy M.F. Yen, Tony H.H. Chen

Research output: Contribution to journalReview articlepeer-review

315 Citations (Scopus)


Eight randomized controlled trials of mammography screening have been conducted to date. In addition to evaluating the efficacy of screening with an experimental design, the trials provided investigators with access to information about breast cancers much earlier in their development than had previously been available. The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality.

Original languageEnglish
Pages (from-to)793-806
Number of pages14
JournalRadiologic Clinics of North America
Issue number5
Publication statusPublished - Sept 2004
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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