The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells

Chi Hao Wu; Hsiao Wen Huang; Jer An Lin; Shang Ming Huang; Gow Chin Yen

doi:10.1016/j.jnutbio.2010.05.002

The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells

Chi Hao Wu, Hsiao Wen Huang, Jer An Lin, Shang Ming Huang, Gow Chin Yen

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

In this study, the effects of phenolic acids [caffeic acid (CA), ferulic acid, m-coumaric acid, and chlorogenic acid] on methylglyoxal (MG)-induced protein glycation were investigated in vitro. Sodium dodecyl sulfate polyacrylamide gel electrophoresis and advanced glycation end products (AGEs)-specific fluorescence showed that MG-mediated protein modification was enhanced dose-dependently by CA (P

Original language	English
Pages (from-to)	585-594
Number of pages	10
Journal	Journal of Nutritional Biochemistry
Volume	22
Issue number	6
DOIs	https://doi.org/10.1016/j.jnutbio.2010.05.002
Publication status	Published - Jun 2011
Externally published	Yes

Keywords

Advanced glycation end products
Caffeic acid
Inflammation
Methylglyoxal
Oxidative stress
Pro-glycation

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Molecular Biology
Endocrinology, Diabetes and Metabolism
Nutrition and Dietetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jnutbio.2010.05.002

Cite this

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title = "The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells",

abstract = "In this study, the effects of phenolic acids [caffeic acid (CA), ferulic acid, m-coumaric acid, and chlorogenic acid] on methylglyoxal (MG)-induced protein glycation were investigated in vitro. Sodium dodecyl sulfate polyacrylamide gel electrophoresis and advanced glycation end products (AGEs)-specific fluorescence showed that MG-mediated protein modification was enhanced dose-dependently by CA (P",

keywords = "Advanced glycation end products, Caffeic acid, Inflammation, Methylglyoxal, Oxidative stress, Pro-glycation",

author = "Wu, {Chi Hao} and Huang, {Hsiao Wen} and Lin, {Jer An} and Huang, {Shang Ming} and Yen, {Gow Chin}",

year = "2011",

month = jun,

doi = "10.1016/j.jnutbio.2010.05.002",

language = "English",

volume = "22",

pages = "585--594",

journal = "Journal of Nutritional Biochemistry",

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TY - JOUR

T1 - The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells

AU - Wu, Chi Hao

AU - Huang, Hsiao Wen

AU - Lin, Jer An

AU - Huang, Shang Ming

AU - Yen, Gow Chin

PY - 2011/6

Y1 - 2011/6

N2 - In this study, the effects of phenolic acids [caffeic acid (CA), ferulic acid, m-coumaric acid, and chlorogenic acid] on methylglyoxal (MG)-induced protein glycation were investigated in vitro. Sodium dodecyl sulfate polyacrylamide gel electrophoresis and advanced glycation end products (AGEs)-specific fluorescence showed that MG-mediated protein modification was enhanced dose-dependently by CA (P

AB - In this study, the effects of phenolic acids [caffeic acid (CA), ferulic acid, m-coumaric acid, and chlorogenic acid] on methylglyoxal (MG)-induced protein glycation were investigated in vitro. Sodium dodecyl sulfate polyacrylamide gel electrophoresis and advanced glycation end products (AGEs)-specific fluorescence showed that MG-mediated protein modification was enhanced dose-dependently by CA (P

KW - Advanced glycation end products

KW - Caffeic acid

KW - Inflammation

KW - Methylglyoxal

KW - Oxidative stress

KW - Pro-glycation

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DO - 10.1016/j.jnutbio.2010.05.002

M3 - Article

C2 - 20951562

AN - SCOPUS:79955856266

SN - 0955-2863

VL - 22

SP - 585

EP - 594

JO - Journal of Nutritional Biochemistry

JF - Journal of Nutritional Biochemistry

IS - 6

ER -

The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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