The knowns and unknowns of callose biosynthesis in terrestrial plants

Yves S.Y. Hsieh, Mu-Rong Kao, Matthew R. Tucker

Research output: Contribution to journalArticlepeer-review


Callose, a linear (1,3)-β-glucan, is an indispensable carbohydrate polymer required for plant growth and development. Advances in biochemical, genetic, and genomic tools, along with specific antibodies, have significantly enhanced our understanding of callose biosynthesis. As additional components of the callose synthase machinery emerge, the elucidation of molecular biosynthetic mechanisms is expected to follow. Short-term objectives involve defining the stoichiometry and turnover rates of callose synthase subunits. Long-term goals include generating recombinant callose synthases to elucidate their biochemical properties and molecular mechanisms, potentially culminating in the determination of callose synthase three-dimensional structure. This review delves into the structures and intricate molecular processes underlying callose biosynthesis, emphasizing regulatory elements and assembly mechanisms.
Original languageEnglish
Article number109103
JournalCarbohydrate Research
Publication statusPublished - Apr 2024


  • (1,3)-β-glucan
  • Callose
  • Callose synthase
  • Polysaccharide biosynthesis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry


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