氧氣輔助慢性阻塞性肺部疾病患者運動訓練及行走時之成效

Most patients with chronic obstructive pulmonary diseases (COPD) have musculoskeletal dysfunction. Due to the trainings of skeletal muscles of extremities and endurance exercise can retard the exercise acidemia and reduce respiratory work it is more necessary than training respiratory muscles. The efficacy of physiology in musculoskeletal training had been proved but we still need future research and study for the systemic inflammatory response and exercise induced oxidation.
Ambulatory oxygen therapy not only could improve endurance exercise test and exercise tolerance (such as walking distance or step test) but also could improve Borg scale, SaO2/PaO2 and ventilation during exercise test. This concept can be applied to assess the indication of ambulatory oxygen therapy and the dosage of oxygen use.
Long term continuous oxygen therapy for patients with COPD complicated with severe hypoxemia is indicated either at rest or during exercise. However there was no enough research data to support the following practice, thus we moderately suggested those concepts as following: in walking test with those COPD patients who are not indicated for long term continuous oxygen therapy, if hypoxemia was induced observed during exercise test, oxygen should be used during exercise training or domiciliary activity; if hypoxemia was not observed, supplemental oxygen still was needed during exercise training or activity for elevating exercise training dosing.