Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor

Medicine and Dentistry

• Programmed Cell Death 100%
• DNA Damage Response 100%
• Atypical Teratoid Rhabdoid Tumor 100%
• In Vitro 16%
• Tumor Cell 16%
• Short Hairpin RNA 11%
• Central Nervous System 5%
• Clinical Trial 5%
• Survival Rate 5%
• Biological Marker 5%
• Malignant Neoplasm 5%
• Cancer 5%
• Cell Proliferation 5%
• Cell Death 5%
• RNA Sequence 5%
• Western Blot 5%
• Overall Survival 5%
• Tumor Progression 5%
• Colony Formation 5%
• DNA Repair 5%
• Growth Inhibition 5%
• Transcription Initiation 5%
• Ribonucleotide Reductase 5%
• Genomic Instability 5%
• Molecular Profiling 5%
• Rhabdoid Tumor Cell Line 5%
• Cell Migration 5%
• Recombinant DNA 5%

Biochemistry, Genetics and Molecular Biology

• DNA Damage Response 100%
• RRM2 100%
• Small Hairpin RNA 14%
• Cell Migration 7%
• Mouse Model 7%
• DNA Repair 7%
• Clinical Trial 7%
• Cell Proliferation 7%
• Overall Survival 7%
• Survival Rate 7%
• In Vitro Study 7%
• Colony Formation 7%
• Transcription Initiation 7%
• Genome Instability 7%
• RNA Sequence 7%
• Cell Death 7%
• Tumor Progression 7%
• Western Blot 7%
• Ribonucleotide Reductase 7%
• Growth Inhibition 7%
• Recombinant DNA 7%

Pharmacology, Toxicology and Pharmaceutical Science

• Atypical Teratoid Rhabdoid Tumor 100%
• Short Hairpin RNA 11%
• Clinical Trial 5%
• Survival Rate 5%
• Biological Marker 5%
• Malignant Neoplasm 5%
• Western Blot 5%
• RNA-Sequencing 5%
• Mouse Model 5%
• Ribonucleotide Reductase 5%
• Tumor Growth 5%
• Overall Survival 5%
• Recombinant DNA 5%