T2-weighted fast MR imaging with true FISP versus HASTE: Comparative efficacy in the evaluation of normal fetal brain maturation

H. W. Chung, C. Y. Chen, R. A. Zimmerman, K. W. Lee, C. C. Lee, S. C. Chin

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100 Citations (Scopus)


OBJECTIVE. This study compares the relative efficacy of two fast T2-weighted MR imaging techniques fast imaging with steady-state free precession (true FISP) and half-Fourier acquisition single-shot turbo spin-echo (HASTE) in the evaluation of the normal fetal brain maturation during the second and third trimesters of gestation. SUBJECTS AND METHODS. The brain maturation of 10 normal nonsedated fetuses (5 during the second trimester and 6 during the third trimester of gestation [1 fetus underwent 2 examinations]) was examined by both techniques using a Vision+ 1.5-T MR system. We specifically looked for developing events, including white matter myelination, neuronal migration, and cortical sulcation. Image quality was graded according to the presence or absence of undesirable blurring. RESULTS. The specific absorption rate was lower for true FISP than for HASTE by a factor of 3 at equivalent imaging conditions. HASTE and true FISP provide comparable image quality in the second trimester when myelination of the cerebrum has not begun. Neuronal migration could be recognized as hypodense bands on both sequences during the second trimester. Myelination beginning at the third trimester was better delineated with true FISP than with HASTE because of point spread function-related blurring effects inherent in HASTE that hampered visualization of short-T2 structures. Cortical sulcation was well delineated by both-sequences. CONCLUSION. With relatively superior image quality and significantly lower radiofrequency absorption than HASTE, true FISP is a safer and more effective alternative in the prenatal evaluation of normal fetal brain.

Original languageEnglish
Pages (from-to)1375-1380
Number of pages6
JournalAmerican Journal of Roentgenology
Issue number5
Publication statusPublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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