Synthesis of (±)-annonelliptine and (±)-anomoline

Chi Ming Chen; Yu Fei Fu; Tsang Hsiung Yang

doi:10.1021/np50125a022

Synthesis of (±)-annonelliptine and (±)-anomoline

Chi Ming Chen, Yu Fei Fu, Tsang Hsiung Yang

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

In order to confirm the structures of annonelliptine [1] and anomoline [2]. chemical synthesis of (±)-1 and (±)-2 has been achieved. Two isomeric alkaloids, (±)-N-northalmeline [3] and (±)-thalmeline [4] were also prepared by a similar approach. The structures of 1 and 2 were confirmed unequivocally by comparison with the synthetic samples. COLOC and nOe nmr spectra were also used to study the structures of these compounds.

Original language	English
Pages (from-to)	1767-1771
Number of pages	5
Journal	Journal of Natural Products
Volume	58
Issue number	11
DOIs	https://doi.org/10.1021/np50125a022
Publication status	Published - Nov 1995
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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AU - Fu, Yu Fei

AU - Yang, Tsang Hsiung

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AB - In order to confirm the structures of annonelliptine [1] and anomoline [2]. chemical synthesis of (±)-1 and (±)-2 has been achieved. Two isomeric alkaloids, (±)-N-northalmeline [3] and (±)-thalmeline [4] were also prepared by a similar approach. The structures of 1 and 2 were confirmed unequivocally by comparison with the synthetic samples. COLOC and nOe nmr spectra were also used to study the structures of these compounds.

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Synthesis of (±)-annonelliptine and (±)-anomoline

Abstract

ASJC Scopus subject areas

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