Synthesis and Biological Evaluation of Some 1‐Substituted 3‐(2‐Perimidyl)ureas

Kang‐Chien ‐C Liu, Hsu‐Shan ‐S Huang

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Some representative 1‐substituted 3‐(2‐perimidyl)ureas were prepared by treatment of 2‐aminoperimidine hydrobromide with the corresponding isocyanates in the presence of triethylamine. A preliminary biological evaluation for their antibacterial and cytotoxic properties revealed that only those compounds which contain a chlorinated substituent at N‐1 exhibited some notable effect.

Original languageEnglish
Pages (from-to)425-426
Number of pages2
JournalArchiv der Pharmazie
Volume321
Issue number7
DOIs
Publication statusPublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmaceutical Science

Fingerprint

Dive into the research topics of 'Synthesis and Biological Evaluation of Some 1‐Substituted 3‐(2‐Perimidyl)ureas'. Together they form a unique fingerprint.

Cite this