Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways

Medicine & Life Sciences

• cyanidin 98%
• Peroxisome Proliferator-Activated Receptors 69%
• Non-alcoholic Fatty Liver Disease 61%
• Mitogen-Activated Protein Kinases 56%
• Oxidative Stress 42%
• Troglitazone 40%
• Antioxidants 15%
• Lipid Metabolism 13%
• Enzyme Activation 9%
• JNK Mitogen-Activated Protein Kinases 8%
• Enzymes 7%
• Extracellular Signal-Regulated MAP Kinases 7%
• Liver 7%
• Genes 5%
• Cell Death 5%
• Transcription Factors 5%
• Down-Regulation 5%

Agriculture & Biology

• peroxisome proliferator-activated receptors 83%
• cyanidin 67%
• mitogen-activated protein kinase 62%
• agonists 53%
• cytotoxicity 49%
• oxidative stress 45%
• antioxidant enzymes 19%
• lipid metabolism 14%
• enzyme activation 8%
• hepatotoxicity 8%
• liver 8%
• cell death 6%
• transcription factors 5%
• genes 4%

Chemical Compounds

• Troglitazone 99%
• Antioxidant Agent 32%
• Protein 23%
• Pharmacological Metabolism 22%
• Lipid 19%
• Apoptotic 16%
• Cell Death 15%
• Oxidative Stress 14%
• Metabolic 11%