Synchronous occurrence of primary neoplasms in the uterus with squamous cell carcinoma of the cervix and adenocarcinoma of the endometrium

Cheng Kuo Lin, Mu Hsien Yu, Ta Wei Chu, Hung Cheng Lai

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Objective: Synchronous primary malignant neoplasms of the uterus are uncommon. Patients with synchronous cervical and endometrial cancers are even rarer. We describe a case of cervical squamous cell carcinoma and endometrial endometrioid adenocarcinoma occurring simultaneously in a 47-year-old woman presenting with massive menstrual bleeding. The concept of synchronous primary malignancies of the genital tract is also reviewed in this report. Case Report: A 47-year-old overtly obese female presented with menometrorrhagia of over 6 months' duration. Pelvic examination detected a large cervix but apparently normal externals. Magnetic resonance imaging revealed a mass over the cervical region and endometrial lesions in the uterine cavity. Surgical exploration disclosed a cervical tumor and erosion of the endometrium. The pathologic findings were compatible with synchronous occurrence of primary neoplasms in the uterus with squamous cell carcinoma of the cervix and adenocarcinoma of the endometrium. Conclusion: Synchronous genital tract neoplasms are rare but cause more clinical problems than a single neoplasm. It is practical to pay more attention to the differential diagnosis of primary and metastatic tumors. The second primary cancer that occurs in an individual with endometrial cancer may offer an opportunity for early detection. The prognosis for a patient with synchronous gynecologic malignancies does not seem to be worse.

Original languageEnglish
Pages (from-to)336-339
Number of pages4
JournalTaiwanese Journal of Obstetrics and Gynecology
Volume45
Issue number4
DOIs
Publication statusPublished - Dec 2006
Externally publishedYes

Keywords

  • Cervical cancer
  • Endometrial cancer
  • Synchronous primary malignancies

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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