Structures of dimeric, trimeric, and tetrameric procyanidins from Areca catechu L

Gen Ichiro Nonaka, Feng Lin Hsu, Itsuo Nishioka

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111 Citations (Scopus)

Abstract

Two procyanidin tetramers, two trimers, and a dimer which is a structural isomer of procyanidin B-1, along with (+)-catechin, (-)-epicatechin, and procyanidins A-1, B-1, and B-2, have been isolated pure from the seed of Areca catechu L., and their 1H and 13C n.m.r. spectral data, combined with degradative studies on their reactions with toluene-α-thiol, have established that they all, except for procyanidin B-2, have the C(4)-to-C(8) [or C(6)]-linked (-)-epicatechin stereochemistry [C(2), C(3): cis] in the upper units, and the (+)-catechin stereochemistry [C(2), C(3): trans] in the terminal (lower) units.

Original languageEnglish
Pages (from-to)781-783
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number15
DOIs
Publication statusPublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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