Streptococcal toxic shock syndrome complicating varicella in children

Yao Jong Yang, Ching Chuan Liu, Shih Min Wang, Chao Ching Huang, Jiunn Jong Wu

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


The most common complication in children with varicella is cutaneous superimposed infection with pyogenic bacteria. Group A β-hemolytic streptococci, which are known to cause life-threatening infections in both previously healthy children and those with underlying diseases, are the most frequently associated pathogens. A newly recognized disease, called streptococcal toxic shock syndrome, is associated with severe morbidity and mortality. We report a 3-year-old boy with a diagnosis of this syndrome who presented with increasing fever, vomiting, and lethargy 7 days after the development of a classic varicella skill lesion. In spite of aggressive fluid supply, administration of inotropic agents, and cardiopulmonary resuscitation, a rapidly deteriorating clinical course led to death 4 hours after hospitalization. This is the first report of this association in Taiwan. Pediatricians evaluating children with varicella must be mindful of the potential for Group A β-hemolytic streptococcal infection.

Original languageEnglish
Pages (from-to)749-753
Number of pages5
JournalJournal of the Formosan Medical Association
Issue number9
Publication statusPublished - Sept 1997
Externally publishedYes


  • Group A β-hemolytic streptococci
  • Streptococcal toxic shock syndrome
  • Varicella

ASJC Scopus subject areas

  • General Medicine


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