Straightforward access to biocompatible poly(2-oxazoline)-coated nanomaterials by polymerization-induced self-assembly

Dao Le, Friederike Wagner, Masanari Takamiya, I-Lun Hsiao, Gabriela Gil Alvaradejo, Uwe Strähle, Carsten Weiss, Guillaume Delaittre

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


We report the synthesis of poly(2-ethyl-2-oxazoline)-based (PEtOx) nanoobjects by polymerization-induced self-assembly (PISA). First, well-defined PEtOx macromolecular chain transfer agents were synthesized by cationic ring-opening polymerization and click chemistry. The photoinitiated PISA of 2-hydroxypropyl methacrylate mediated by these PEtOx produced nanoobjects spanning the full range of core-shell morphologies. The nanoparticles exhibited high biocompatibility and stealth properties in vitro or in vivo, as well as thermoresponsive behavior.

Original languageEnglish
Pages (from-to)3741-3744
Number of pages4
JournalChemical Communications
Issue number26
Early online dateMar 12 2019
Publication statusPublished - 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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