Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case

Jinn Li Wang; Tsong Yih Ou; Chun Nan Chen; Ein Yiao Shen

Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case

Jinn Li Wang
, Tsong Yih Ou
, Chun Nan Chen
, Ein Yiao Shen

Research output: Contribution to journal › Article › peer-review

Abstract

We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.

Original language	English
Pages (from-to)	146-148+161
Journal	Acta Paediatrica Taiwanica
Volume	48
Issue number	3
Publication status	Published - May 2007

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Hyperbilirubinemia
Sepsis
Steroid

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Cite this

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title = "Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case",

abstract = "We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.",

keywords = "Hyperbilirubinemia, Sepsis, Steroid",

author = "Wang, \{Jinn Li\} and Ou, \{Tsong Yih\} and Chen, \{Chun Nan\} and Shen, \{Ein Yiao\}",

year = "2007",

month = may,

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pages = "146--148+161",

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T1 - Steroid use in sepsis-induced conjugated hyperbilirubinemia

T2 - Report of one case

AU - Wang, Jinn Li

AU - Ou, Tsong Yih

AU - Chen, Chun Nan

AU - Shen, Ein Yiao

PY - 2007/5

Y1 - 2007/5

N2 - We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.

AB - We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.

KW - Hyperbilirubinemia

KW - Sepsis

KW - Steroid

UR - https://www.scopus.com/pages/publications/34548811919

UR - https://www.scopus.com/pages/publications/34548811919#tab=citedBy

M3 - Article

C2 - 17912987

AN - SCOPUS:34548811919

SN - 1608-8115

VL - 48

SP - 146-148+161

JO - Acta Paediatrica Taiwanica

JF - Acta Paediatrica Taiwanica

IS - 3

ER -

Steroid use in sepsis-induced conjugated hyperbilirubinemia: Report of one case

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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