Stereotactic internal irradiation for cystic craniopharyngiomas: A 6-year experience

Fourteen adults and 4 children with cystic craniopharyngiomas were treated with stereotactic β-irradiation during a 6-year period. Of these patients, 10 were primary cases, and 8 were recurrences after previous major surgery. Radioactive phosphorus (³²P) or yttrium (⁹⁰Y) in colloidal forms were used as the radiation agents. Cyst volumes (10-130 ml) were assessed intraoperatively by the ⁹⁹Tc radiodilution method. According to our treatment program, the radiation dose to the cyst wall was 20,000 rad and the total irradiation time 2 weeks. The follow-up period ranged from 1 to 6 years, with an average of 3.8 years. Postoperative shrinkage of the cysts and clinical improvement were observed in most patients. Pertinent clinical data and results of treatment are described.